desmoplasia

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desmoplasia

[‚dez·mə′plā·zhə]
(medicine)
The formation and proliferation of connective tissue, frequently in the growth of tumors.
The formation of adhesions.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Immunohistochemistry can be useful to identify or delineate subtle melanocytic proliferations such as desmoplastic melanoma, lentigo maligna, and subtle invasion in areas of fibrosis or inflammation underlying melanoma in situ.
On CT scan, a carcinoid tumor affecting the mesentery appears as a soft tissue mass with calcification and desmoplastic stranding, which produces a "sunburst" appearance.
PDL1 expression in desmoplastic melanoma is associated with tumor aggressiveness and progression.
With microcystic adnexal carcinoma it is difficult to differentiate from infiltrating basal cell carcinoma and desmoplastic trichoepithelioma.
It came after she was diagnosed in 2011 with desmoplastic small round cell tumour, or DSRCT, having endured terrible back pain while on holiday.
As far as we know only 37 cases were previously described in the literature under different names like: desmoplastic nested spindle cell tumor of the liver, ossifying malignant mixed epithelial and stromal tumor of the liver [3], nested stromal epithelial tumor of the liver and ossifying stromal-epithelial tumor [4], It was first described by Ishak et al.
Caption: Figure 4: A neoplasm with an infiltration pattern is identified in small- and medium-sized nodules, surrounded by desmoplastic stroma.
Desmoplastic melanoma (DM) represents a relatively rare variant of cutaneous melanoma with a clinical course more similar to soft-tissue sarcoma [24].
Desmoplastic small round cell tumor (DSRCT) is a rare cancer which predominantly affects males averaging 21 years of age at the time of diagnosis [1].
Oral manifestations of TS occur in 11% of affected subjects, and oral abnormalities include the presence of delayed eruption, bifid uvula, enamel hypoplasia, cystic hyperostosis, hyperplasia, enamel pitting, haemangioma, multiple osteomas, cleft lip and palate, and desmoplastic fibromas (DF) [2, 4].
Wide nests of tumor cells can be seen invading as well as a desmoplastic reaction to the nests and the lymphoplasmacytic host response.
Study Author Age Location (1) Cervoni 71 R cerebellar hemisphere (2) Cervoni 67 L cerebellar hemisphere (3) Jaiswal 65 Vermis (4) Huppmann 65 R cerebellar hemisphere (5) Yong 71 4th ventricle (6) Kepes 73 R cerebellar hemisphere (7) Ramsay 66 Cerebellar hemisphere (8) Ramsay 65 Cerebellar hemisphere (9) Liang 72 R cerebellar hemisphere (10) Sajko 62 R superior cerebellar peduncle (11) Aljoghaiman 51 R middle cerebellar peduncle + (current case) superior vermis Study Pathology (1) Not specified (2) Not specified (3) Medulloblastoma with glial differentiation (4) Classic subtype (5) Classic subtype (6) Classic subtype (7) Classic subtype (8) Desmoplastic subtype (9) Classic subtype (10) Desmoplastic subtype (11) Classic subtype (SHH subgroup)