Deoxycorticosterone

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deoxycorticosterone

[dē¦äk·sē‚kȯrd·ə′kä·stə‚rōn]
(biochemistry)
C21H30O3 A steroid hormone secreted in small amounts by the adrenal cortex.

Deoxycorticosterone

 

(also cortexone), an intermediate product in the biosynthesis of hormones of the adrenal cortex. Formed primarily from progesterone, it is a mineralocorticoid, that is, an active regulator of mineral metabolism, and in this connection the most stable preparation of deoxycorticosterone is deoxycorticosterone acetate, which is used in medicine.

References in periodicals archive ?
The effects of fever, of desoxycorticosterone and of estrogen on clinical patients with metastatic carcinoma of the prostate.
Two options are available: fludrocortisone acetate (Florinef) and desoxycorticosterone pivalate (DOCP, commonly known by the brand name Percorten-V).
In a basic physiologic study that looked at isolated aortas from both normotensive and desoxycorticosterone acetate (DOCA)-salt hypertensive rats, it was found that "changes in extracellular magnesium concentration differentially alter endothelin-1-induced contraction in aortae from normotensive and hypertensive rats, possibly by interfering with calcium utilization during contraction.