dextromethorphan hydrobromide

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dextromethorphan hydrobromide

[¦dek·strō·mə¦thȯr·fən‚hī·drō′brō‚mīd]
(pharmacology)
C18H25NO·HBr·H2O White crystals or a crystalline powder; soluble in alcohol and chloroform; used in medicine.
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Teens who are in the know talk about using specific dosages to reach different "plateaus": the first, a mild stimulant effect (100-200 mg); the second, intoxication with mild hallucinations (200-400 mg); the third and most sought after, an "out of the body" experience (300-600 mg, or 14-16 Coricidin HBP Cough/Cold tablets, each of which contains 30 mg dextromethorphan hydrobromide).
While there is ample literature on the classically used agents, folic acid and folinic acid, much of what is known about vitamin A and dextromethorphan come from basic science investigations and expert opinion.
Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.
According to (http://www.drugabuse.gov/publications/drugfacts/cough-cold-medicine-abuse) NIDA , users of high doses of dextromethorphan described effects in the range of mild stimulation or intoxication and at high dosages sensations of physical distortion and hallucinations.
[q.sub.e] is equilibrium adsorbed quantity (mg of adsorbate per gram of adsorbent) calculated as [q.sub.e] = V([C.sub.0] - [C.sub.e])/W, where "V" is total volume in litre and W is the quantity of AC in grams; [C.sub.0] (mg/L) is the initial quantity of dextromethorphan and [C.sub.e] is the concentration after the adsorption.
"With quinidine, we can use smaller dosages of dextromethorphan" than might be required if the drug were used by itself and thereby avoid the lethargy that could occur in patients who might require larger dosages of dextromethorphan without quinidine, he said in an interview.
After 10 weeks, the 93 patients on dextromethorphan plus quinidine had their average neuropsychiatric inventory domain score for agitation and aggression cut roughly in half, compared with baseline, compared with about a 25% drop in average score among 66 control patients, a statistically significant difference for the study's primary endpoint, Dr.
"Like every medication, dextromethorphan has side effects," Dr.
A single dose of dextromethorphan, however, reduced the women's pain response to the tests-with women with fibromyalgia benefiting as much as those without the condition.
Tests show the victims' stomachs contained dextromethorphan, a synthetic morphine derivative used in cough syrup that can have mind-altering effects if consumed in large quantities.