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Related to diabetic neuropathy: diabetic diet, Diabetic Peripheral Neuropathy


Any disease affecting neurons.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a functional weakness of the nervous system accompanied by a decrease in the absolute threshold (also called the stimulus, or sensitivity, threshold); the condition is frequently congenital.

Neuropathy arises as a disturbance in the function of the autonomic nervous system owing to deleterious influences on the fetus as a whole (for example, infection in the pregnant mother, trauma, or poisoning) or on the individual embryonic cells (as occurs when the parents suffer from alcoholism). Family circumstances, upbringing, and illnesses suffered by the infant play a role in the pathogenesis of neuropathy. The symptoms usually emerge in childhood or adolescence. When neuropathy occurs in early childhood, disturbances of sleep and appetite are most characteristic; the infant has difficulty in falling asleep, awakes easily, suckles poorly, and frequently spits up. Later, vomiting occurs, and either diarrhea or constipation develop.

From the preschool years on, increased general excitability and the rapid onset of fatigue and exhaustion are observed, in addition to continued disturbances of sleep and appetite. Children who suffer from neuropathy blush easily in response to irritation. Motor hyperactivity, nervous tics, and stammering are frequent. In adolescence, autonomic-vascular instability becomes more acute, as evidenced by frequently occurring nervous palpitation, abrupt shifts in blood pressure, headaches, dizzy spells, and fainting spells. The prognosis is favorable, with the neuropathic symptoms usually disappearing with age.


Simson, T. Nevropatii, psikhopatii i reaktivnye sostoianiia mladencheskogo vozrasta. Moscow-Leningrad, 1929.
Sukhareva, G. E. Klinicheskie lektsii po psikhiatrii detskogo vozrasta, vol. 2. Moscow, 1959.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Primarily diabetic neuropathy is the disorder of sensory nerves thus explaining the reason for pain, tingling, pricking sensations and numbness in the beginning followed much later by motor nerve dysfunction17.
Various studies have shown the difference in RNFL thickness in diabetic patients, as compared to normal age matched population.9 Diabetic neuropathy is supposed to affect neurons, and thus, measurement of RNFL thickness in patients with DM can be utilized to diagnose patients with, or at risk for development of diabetic neuropathy.
Diabetic neuropathy (DN) is a set of heterogeneous clinical syndromes that affect distinct regions of the nervous system, singly or combined.
However, very little research has considered the correlation between NCS parameters, HbAlc, and subclinical diabetic neuropathy. The objectives of the present study were to evaluate various nerve conduction parameters in neurologically asymptomatic Diabetic patients with an attempt to analyze their value in the early detection of subclinical diabetic neuropathy and also to see if any correlation exists between nerve conduction parameters and the levels of HbAlc.
Acute painful diabetic neuropathy: an uncommon, remittent type of acute distal small fibre neuropathy.
The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study.
Groups Tx1 and Tx2 comprised patients with advanced complications of diabetes including severe diabetic neuropathy and end-stage diabetic nephropathy.
They demonstrated that increased glucose metabolism due to hyperglycemia resulted in increased oxidative stress, mitochondrial dysfunction, and cell death in both in vitro and in vivo models of diabetic neuropathy [27].
Diabetic neuropathy is a condition in which the peripheral nerves are damaged due to high blood glucose and vascular risk factors like high blood pressure, and lipids as well as being overweight.
Diabetic neuropathy appears to occur more commonly in people with poor control of their blood sugar and these other risk factors.
Barohn, "Diabetic neuropathy part 1: overview and symmetric phenotypes," Neurologic Clinics, vol.
Diabetic neuropathy has been defined as the presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after the exclusion of other causes, which is the most common complication of diabetes, affecting 30-50% of individuals with diabetes mellitus.