specificity

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specificity

[‚spes·ə′fis·əd·ē]
(chemistry)
The selective reactivity that occurs between substances, such as between an antigen and its corresponding antibody.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
A limitation of this study was the inclusion of a small number of TN samples, only 6 -12 with the 5-[micro]g/L DrugTest 5000 and 1- and 2-[micro]g/L confirmation cutoffs, to adequately evaluate diagnostic specificity. On the basis of previous reports, more TN samples were expected over the 22-h collection period.
1 clearly show that serum creatinine changes are more useful for diagnostic purposes than [DELTA]Cys; a difference of 0.15 mg/dL (13.2 [micro]mol/L) (around 15%) shows good diagnostic accuracy, but even smaller differences [0.10 mg/dL (8.8 [micro]mol/L) and 0.05 mg/dL] perform better than Cys in detecting CIN--albeit with a decreasing diagnostic specificity [93% for a difference of 0.15 mg/dL (13.2 [micro]mol/L) and 86% and 76%, respectively, for differences of 0.10 and 0.05 mg/dL].
Third, the primary aim of using a [delta] criterion has been to provide improved diagnostic specificity, compared with a single measurement and use of the 99th-percentile reference value (1, 11-13).
In influenza A diagnosis IAVchip DNA microarray and real-time PCR demonstrated equal diagnostic specificity (98.85%), while the same characteristic of RT-PCR was 96.40%.
[13] Multiple studies agree that neutrophil CD64 has high diagnostic specificity and sensitivity.
This allows manipulation of cut-off points to improve the diagnostic specificity of sIgE; the higher the chosen diagnostic cut-off level, the more likely the diagnosis of allergy becomes.
Despite the overlap of ENA's across CTD's four of the antibodies are considered as diagnostic markers for SLE (Sm and Ribo-P), PSS (Scl70) and autoimmune myositis (Jo-1) due to their high diagnostic specificity for those diseases (9).
Although serum anti-lectin antibody detection stands with excellent sensitivity and specificity found in several studies but diagnostic specificity of anti-lectin antibodies in other specimens is yet to be established.
This is based on the low diagnostic ability rating of 8/157 (5.1%), a diagnostic sensitivity of 20% and a high diagnostic specificity level of 96.6%.
(20) However, there is evidence, especially in subjects with very early or undifferentiated arthritis, that use of both RF and anti-CCP testing can improve diagnostic specificity with a minimal loss of sensitivity.
Do you mean to question diagnostic specificity of psychiatric disorders?
(1) Research over the past several years has focused on developing other tests that have increased diagnostic specificity over the RF test.

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