Serum diamine oxidase
activity in patients with histamine intolerance.
The EUF improved the morphological structure and barrier function of the intestine in the present study, which is evidenced by higher villous height and lower concentrations of D-lactate and diamine oxidase
. As the markers of intestinal integrity, lower serum diamine oxidase
and D-lactate contents released from upper villi of the small intestine showed smaller damage of intestinal integrity [47, 48].
The levels of TNF-a, IL-6, IL-1[sz], and diamine oxidase
(DAO) were determined by enzyme-linked immunosorbent assay (ELISA) according to the manufacturer's instructions (R&D, USA), and the concentrations of cytokines were determined spectrophotometrically by the absorbance at 450 nm.
or DAO is responsible for breaking down dietary histamines and to a lesser extent, endogenous histamine.
Two oxime compounds, 1-(3-methylsulfanyl-[1,2,4]triazin-5-yl)- ethanone oxime (2a) and 1-(3-methylsulfanyl- [1,2,4]triazin-5-yl)-propan-1-one oxime (2b) displayed only a very weak effect on pea diamine oxidase
. They were found to be non-competitive inhibitors characterized by high Ki values of 14 and 16 mM, respectively.
(DAO) level was measured in serum samples using a rat specific ELISA kit following manufacturer's instructions.
: an overview of historical, biochemical and functional aspects.
Rikkers, "The effect of the route of nutrient delivery on gut structure and diamine oxidase
levels," Journal of Parenteral and Enteral Nutrition, vol.
Stereochemistry of reactions catalyzed by L-lysine decarboxylase and diamine oxidase
. Phytochemistry 18:771.
After histamine is methylated by HNMT, it is further metabolized by diamine oxidase
or monoamine oxidase-B (MAO-B) (Maintz & Novak, 2001).
Plasma diamine oxidase
, D-xylose, nitric oxide synthase, and NOx concentrations
Highly efficient purification of porcine diamine oxidase