diamine oxidase


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diamine oxidase

[′dī·ə‚mēn ′äk·sə‚dās]
(biochemistry)
A flavoprotein which catalyzes the aerobic oxidation of amines to the corresponding aldehyde and ammonia.
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References in periodicals archive ?
Serum diamine oxidase activity in patients with histamine intolerance.
The EUF improved the morphological structure and barrier function of the intestine in the present study, which is evidenced by higher villous height and lower concentrations of D-lactate and diamine oxidase. As the markers of intestinal integrity, lower serum diamine oxidase and D-lactate contents released from upper villi of the small intestine showed smaller damage of intestinal integrity [47, 48].
The levels of TNF-a, IL-6, IL-1[sz], and diamine oxidase (DAO) were determined by enzyme-linked immunosorbent assay (ELISA) according to the manufacturer's instructions (R&D, USA), and the concentrations of cytokines were determined spectrophotometrically by the absorbance at 450 nm.
Diamine oxidase or DAO is responsible for breaking down dietary histamines and to a lesser extent, endogenous histamine.
Two oxime compounds, 1-(3-methylsulfanyl-[1,2,4]triazin-5-yl)- ethanone oxime (2a) and 1-(3-methylsulfanyl- [1,2,4]triazin-5-yl)-propan-1-one oxime (2b) displayed only a very weak effect on pea diamine oxidase. They were found to be non-competitive inhibitors characterized by high Ki values of 14 and 16 mM, respectively.
Diamine oxidase (DAO) level was measured in serum samples using a rat specific ELISA kit following manufacturer's instructions.
Rikkers, "The effect of the route of nutrient delivery on gut structure and diamine oxidase levels," Journal of Parenteral and Enteral Nutrition, vol.
Stereochemistry of reactions catalyzed by L-lysine decarboxylase and diamine oxidase. Phytochemistry 18:771.
After histamine is methylated by HNMT, it is further metabolized by diamine oxidase or monoamine oxidase-B (MAO-B) (Maintz & Novak, 2001).