In order to identify diapedesis
mechanisms, we sought soluble factors secreted by OE-MSCs.
, the white blood cell changes its shape in order to squeeze between or through the epithelial cells that form the walls of the blood vessel.
Recent studies show that oxidized phospholipids favor monocyte binding to endothelial cells, thus promoting diapedesis
from the blood stream .
Adhesion receptor CD11b/CD18 contributes to neutrophil diapedesis
across the bovine blood-milk barrier.
A microscopic examination revealed a slight swelling and minor bleeding lesions of lung parenchyma, and pulmonary vascular engorgement in violation of the permeability of the walls and diapedesis
of red blood cells in the surrounding tissue.
Absence of dry cow therapy regime could possibly be the major factor contributing to high prevalence at early lactation and early infection associated with delayed diapedesis
of neutrophils in to the mammary gland (Schalm et al., 1971).
In addition to acting as neurotransmitters, CGRP and substance P serve as vasodilators, increasing vascular flow and permeability (diapedesis
) and stimulating plasma extravasation and leukocyte migration into tissues (transmigration).