Men exposed to dibromochloropropane
, certain pesticides, alcohol, lead, and solvents, as well as men employed in the aluminum industry and in saw mills, father fewer sons than expected (Davis et al.
Based on an assessment algorithm used by Jarrell (2002), there is reasonably strong evidence linking reduced sex ratios and environmental exposures of dioxin, dibromochloropropane, and hexachlorobenzene (HCB).
1995) Radiation Background ionizing radiation (Saadat 2003) Occupation Infertility treatment Lifestyle Abbreviations: DBCP, dibromochloropropane; PCDFs, polychlorinated dibenzofurans.
Diazinon, dimethoate, chlorpyrifos, carbaryl, DDE, DDT, diuron, and oxamyl have been detected in surface water (concentration range = 0.1-2.8 [micro]g/L), and 1,2-dichloropropane, 2,4-D, atrazine, dibromochloropropane
, ethylene dibromide, heptachlor, simazine, bromacil, diuron, and hexazinone in well waters (California Department of Pesticide Regulation 2005b).
In the late 1970s the nemarocide dibromochloropropane
affected more than 26,000 plantation workers in 12 countries; 64% had low sperm concentrations and 28% were involuntarily childless (Goldsmith 1997; Slutsky et al.
In 1977, men exposed to dibromochloropropane
(DBCP), a pesticide that is now banned in the United States, were found to be azoospermic and oligospermic (Whorton et al.
1991); and dibromochloropropane
at levels found in manufacturing plants (Huff 1983a).
(DBCP): an 8-year reevaluation of testicular function and reproductive performance.
Our goal was to determine the patient's potential exposure to chemicals known to affect male fertility, namely, dibromochloropropane
(DBCP), lead, boron, cadmium, carbaryl, kepone, methyl mercury, toluene, toluenediamine, and dinitrotoluene.
Safe (1) noted that low sex ratios (proportions male at birth) follow exposure to dioxins, the nematocide dibromochloropropane
(DBCP), and cocktails of unidentified agricultural chemicals.
Sperm count depression in pesticide applicators exposed to dibromochloropropane
. Am J Epidemiol 109(3):346-351 (1979).
Occupational exposures to lead, dibromochloropropane
, ethylene dibromide, and glycol ethers affect sperm production in humans (1,65-68).