dicentric


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dicentric

[dī′sen·trik]
(cell and molecular biology)
Having two centromeres.
References in periodicals archive ?
Among detected structural aberrations the highest presence of gaps, breaks and marker chromosomes was documented, The ring chromosomes and the chromosome fragmentation were present within the C1 only; while dicentric chromosomes were detected in C1 and C2.
The dicentric nature of the metacentric B chromosome of Metaleptea brevicornis adspersa (Acridinae, Acrididae).
A telomere hypothesis of cellular aging has been proposed, where the loss of telomere sequences provides the signal for cells to enter into senescence, leading to the formation of dicentric chromosomes and classical breakage-fusion-bridge (BFB) cycles followed by genome rearrangements and aneuploidy (Pathak & Multani, 2006).
Dicentric, tricentric, bridged, and fragmental chromosomes occurred in high frequency in the groups of 12-20 sec irradiation.
5 Subsequently, it was shown that the supernumerary CES chromosome is dicentric, the result of the duplication of a 2-million base region of the long arm of chromosome 22 (22 pter [right arrow] q 11.
Dicentric chromatids are responsible for bridges and acentric chromatids (fragments).
In males there is no crossing-over; and in females the geometry of the meiotic divisions is such as to exclude the dicentric and acentric recombinant products from the functional egg nucleus.
Rarely were spreads interpreted as exhibiting a translocation, acentric chromosome, or dicentric chromosome.
Others range from pathology and hematology (quantitative genetic scoring of tissue sections from solid tumors or from bone marrow preparations; virtual slide imaging; rare tumor cell detection) to toxicology (DNA damage assessment using the micronucleus test or Comet assay; chromosome aberration testing and automatic scoring of dicentric chromosomes) and even to forensic science (automatic sperm detection in material from crime scenes).
The authors found no difference in the frequency of dicentric and ring chromosomes between these groups.