DES

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DES

DES or diethylstilbestrol (dīˌĕthˌəlstĭlbĕsˈtrôl), synthetic nonsteroid female sex hormone having the same physiological effects as estrogen. In the 1940s and 50s DES was mistakenly believed to reduce the risk of miscarriage and was routinely prescribed for pregnant women believed to be at risk. In fact, it was later found to increase the risk of miscarriage and was then tested in a “morning-after” pill, a contraceptive pill that is taken after intercourse. In the late 1960s and early 70s a group of Boston physicians found that women whose mothers had taken DES during pregnancy had an unusually high rate of vaginal cancer, and it has since been implicated in various reproductive disorders and other conditions in female and male children of such mothers. The use of DES to prevent miscarriage was banned in 1973; its use as a growth accelerator in beef cattle was banned in 1979. It currently finds some use in the hormone treatment of certain types of cancer.
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DES

(communications)
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McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

DES

This article is provided by FOLDOC - Free Online Dictionary of Computing (foldoc.org)

DES

(1) (Digital Entertainment System) See digital media server.

(2) (Data Encryption Standard) A NIST-standard cryptographic cipher that uses a 56-bit key. Adopted by the NIST in 1977, it was replaced by AES in 2001 as the official standard. DES is a symmetric block cipher that processes 64-bit blocks in four different modes of operation, with the electronic code book (ECB) being the most popular.

Triple DES
By adding various multiple-pass methods, Triple DES increased security; for example, encrypting with one key, decrypting the results with a second key and encrypting it again with a third. However, the extra passes added considerable computing time to the process. DES is still used in applications that do not require the strongest security. See cipher, cryptography, NIST, AES and Fortezza.
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References in periodicals archive ?
Ketoconazole has a distinct advantage over diethylstilbestrol in that the former drug reduces testosterone to castrate levels within 48 hours compared with 2 weeks for diethylstilbestrol.
Molecular feminization of mouse seminal vesicle by prenatal exposure to diethylstilbestrol: altered expression of messenger RNA.
METHODS: Female CD-1 mice that were exposed to BPA at 0, 25 ng, 250 ng, or 25 [micro]g/kg body weight (BW)/day or diethylstilbestrol (DES) at 10 ng/kg BW/day (positive control) from gestational day 8 through day 16 of lactation were continuously housed with proven breeder males for 32 weeks starting at 2 months of age.
Washington, May 22 (ANI): Adult women who were exposed prenatally to bisphenol-A (BPA, a chemical commonly used in plastic food containers) or diethylstilbestrol (DES) could be at increased risk of breast cancer, according to a new study in mice.
"Wonder Drug" is a "scientific drama" of how DES (diethylstilbestrol), the world's first drug disaster, harms the lives of a pharmaceutical executive, a feminist doctor and a 30-something newlywed.
* Medical research indicates that daughters of women who took the drug diethylstilbestrol (DES) during the years 1938 through 1971 to prevent miscarriage have an increased risk of developing this disease.
A new Web site provided by he Centers for Disease Control and Prevention offers educational resources about health risks associated with diethylstilbestrol (DES) exposure.
Women in this age group who have a history of cervical cancer, in utero exposure to diethylstilbestrol (DES), or who are immunocompromised should continue screening as long as they are in "reasonably good health and do not have a life-0limiting chronic condition," the new ACS guidelines state.
In the 1940s, physicians began giving diethylstilbestrol (DES) to pregnant women, several million of them in the United States alone.
Diethylstilbestrol (DES), dexamethasone (DEX), cyclophosphamide (CPS), and 2,3,7,8-tetra-chlorodibenzo-p-dioxin (TCDD) are environmental chemicals that produce immunotoxic effects in the thymus, but the mechanism of toxicity has been considered to be different for each compound.
Inspired by real events, "Wonder Drug" is a scientific drama of how DES (diethylstilbestrol), the world's first drug disaster, harms the lives of a pharmaceutical executive, a feminist doctor and a 30-something newlywed across different decades.
"Our serial lot analyses found that PC SPES lots manufactured from 1996 through the middle of 1999 contained indomethacin and diethylstilbestrol and that lots manufactured from the middle of 1999 through August 2001 contained progressively lower amounts of both substances and also had correspondingly decreased antineoplastic activity and estrogenicity," said Dr.