differentiation antigen

differentiation antigen

[dif·ə‚ren·chē¦ā·shən ′ant·i·jən]
(immunology)
A cell surface antigen that is expressed only during a specific period of embryological differentiation.
References in periodicals archive ?
Plasmacytoid dendritic cells (pDC) are the most important cells to connect innate and adaptive immune responses, and also the main source of interferon (IFN)-a.[4] IFN-a can suppress the activity of HBV enhancers,[5] control HBV-posttranscriptional replication,[6],[7],[8] and inhibit HBV nucleocapsid formation in virus replication.[9] It can also limit virus infection by modulating both innate and adaptive immunity, directly activate natural killer (NK) cells to enhance their cytotoxicity to eliminate-infected cells, promote the maturation of DCs, stimulate naive cluster of differentiation antigen 8+ (CD8+) T cells, resulting in clonal expansion and proliferation, and increase expression of chemokines that recruit NK, T and B cells to the site of infection.
(1992) Extensive polymorphism in the extracellular domain of the mouse B cell differentiation differentiation antigen Lyb-2/CD72.
Myeloid cell nuclear differentiation antigen (MNDA) is a nuclear protein that mediates protein-protein interaction specifically with other transcription regulatory proteins.
Ber-MAC3: New monoclonal antibody that defines human monocyte/macrophage differentiation antigen. J Clin Pathol 1991;44:936-945.
2C), CD99, smooth muscle antibody, and bcl-2, but not cytokeratin (Fig-2D), co-factor, epithelial membrane antigen, desmin, myogenic differentiation antigen 1, S-100, actin, or CD68.
The markers were derived during a series of Human Leukocyte Differentiation Antigen workshops.
NY-BR-1, a differentiation antigen of the mammary gland, was first described in 2001 by Jager et al (134) using SEREX (a serologic analysis of recombinant tumor complementary deoxyribonucleic acid expression libraries) in a patient with breast cancer.
They reside in the skin and can be identified by the expression of the monocyte/macrophage and endothelial cell differentiation antigen Ly6C [32].
The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors.
Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma.
Among the many melanoma antigens that have been identified so far, we chose to target the melanocytic differentiation antigen Melan-A/MART-1 and the melanoma overexpressed antigen MELOE-1.