The affected sheep were treated with a single dose of 70,000IU of procaine benzylpenicillin and 70mg of dihydrostreptomycin
sulfate, which is a low cost control method.
(b) MRL refers to the sum of dihydrostreptomycin
After each transfer of larvae, 20 mg/L dihydrostreptomycin
sulfate (Tamura-seiyaku Co., Ltd., Tokyo, Japan) was added to the rearing water to prevent bacterial attachment to the larvae.
Eighteen antimicrobials where studied, those of greater offer in Chile for dairy cows (ampicillin, cefoperazone, ceftiofur, cloxacillin, penicillin G, pirlimycin, nafcillin, dihydrostreptomycin
, gentamicin, neomycin, enrofloxacin, spiramycin, chloramphenicol, lincomycin, oxitetracycline, tetracycline, sulfadimidine and suldadoxin).
Some (amikacin, dihydrostreptomycin
, and kanamycin) are primarily and/or initially cochleotoxic, while others (streptomycin and gentamicin) destroy vestibular hair cells before cochlear hair cells.
A summary follows the committee's evaluations of toxicological and residue data on a variety of veterinary drugs: one fladrenoceptor-blocking agent (carazolol), one anthelminthic agent (doramectin), four antimicrobial agents (dihydrostreptomycin
, streptomycin, neomycin and thiamphenicol), two insecticides (deltamethrin and phoxim), four production aids (estradiol-17fl, progesterone, testosterone and porcine somatotropins) and one tranquilizing agent (azaperone).
After transferring the larvae, 20 mg/L dihydrostreptomycin
sulfate (Tamura-seiyaku Co., Japan) was added to the rearing water to prevent bacterial attachment to the larvae.
The antimicrobial activity was evaluated against strains from the Culture Collection of Microorganisms of Bahia (CCMB): Escherichia coli CCMB261 sulphonamide resistant, Staphylococcus aureus CCMB262 streptomycin and dihydrostreptomycin
resistant, Pseudomonas aeruginosa CCMB268 and Candida albicans CCMB266.
(2)] showed strong interference from neomycin, gentamicin, tobramycin, and paromomycin but relatively little interference from kanamycin, geneticin, streptomycin, amikacin, and dihydrostreptomycin
In response, researchers modified the drug's molecule and created dihydrostreptomycin
. Unlike its predecessor, dihydrostreptomycin
is much more cochleotoxic than it is vestibulotoxic; in fact, it is almost exactly as cochleotoxic as streptomycin is vestibulotoxic.
It's important to note that the introduction of specific antimicrobial treatment (dihydrostreptomycin
) and the imposition of corrective measures regarding the leptospirosis control were efficient to reduce the reproductive problems (data not shown).