dihydroxyphenylalanine


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dihydroxyphenylalanine

[¦dī‚hī¦dräk·sē‚fen·əl′al·ə‚nēn]
(biochemistry)
C9H11NO4 An amino acid that can be formed by oxidation of tyrosine; it is converted by a series of biochemical transformations, utilizing the enzyme dopa oxidase, to melanins. Also known as dopa.
References in periodicals archive ?
The modified amino acid, called dihydroxyphenylalanine (DOPA), has two functions.
TH is a key enzyme and serves as the rate-limiting enzyme in DA production, as it could convert dietary tyrosine to L- dihydroxyphenylalanine (L-DOPA), which may in turn be converted by aromatic amino acid decarboxylase (AADC) to the production of DA.
Tyr is known to be the rate-limiting enzyme affecting the production of melanin pigment [52], which oxidates tyrosine to dihydroxyphenylalanine (DOPA) and determines which type of melanin could be synthesized [53].
It's been known for a number of years that a key ingredient of mussel glue is dihydroxyphenylalanine (DOPA).
Catecholamines and dihydroxyphenylalanine in metamorphosing larvae of the nudibranch Phestilla sibogae Bergh (Gastropoda: Opisthobranchia).
The bulk of the urinary dopamine may be from renal production and uptake of dopamine and decarboxylation of circulating dihydroxyphenylalanine (dopa), [23, 24] which is in turn from hydrolysis of tyrosine.