, also called 2,3-Dimercaptopropanol, was developed by British biochemists during World War II as an antidote for lewisite, an obsolete arsenic-based chemical warfare agent.
and DMPS are chelating agents principally involved in the treatment of poisoning by arsenic and polonium-210, respectively.
(British anti-Lewisite; BAL) is used for the treatment of arsenic, gold, and acute mercury poisoning (not effective for chronic mercury poisoning).
La accion del dimercaprol
es de caracter lipofilo; por eso, si se supera la dosis optima, es danino para el SNC.
En los informes de casos de toxicidad secundaria a inyeccion de mercurio metalico se encontraron tratamientos con diferentes quelantes como: 2-3 dimercaptopropano-1-sulfonato (DMPS), acido 2-3 dimercaptosuccinico (DMSA), dimercaprol
(BAL, por la sigla en ingles de British Anti-Lewisite) y penicilamina.
Necrotic tissue and mercury were surgically removed, and the patient was chelated with dimercaprol
is either used alone (arsenic, gold, and acute mercury) or combined with edetate calcium disodium (lead).
Both acute and chronic exposure is treated with chelation with dimercaprol
(BAL), DMSA (succimer), d-penicillamine DMPS (CEHN, 1999; AAP, 2003).
One type contained the anthrax vaccine and the other contained phials of a drug called dimercaprol
which acts as an antidote to heavy metal poisoning.
Other chelation agents include DMPS (Sodium Dimercaptopropanesulfonate) and Dimercaprol
5 mL) was pipetted into plastic tubes, and 10 [micro]L of dimercaprol
solution and 10 [micro]L of 8-hydroxyquinoline solution were added to each tube and mixed.
54 (256) CaEDTA and dimercaprol
chelation (5 d) 9/30/90 End of chelation 0.