Dipeptides

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Related to dipeptide: Muramyl dipeptide

Dipeptides

 

organic substances consisting of two amino acids connected by a peptide bond (—CO—NH—). Optically active, they form crystals of characteristic shape. The isoelectric point, color reactions, and other properties of dipeptides are determined by the amino acids that enter into their composition. Dipeptides are compounds intermediate between polypeptides and amino acids and are formed by the hydrolysis of proteins. Dipeptides consisting of the same L-amino acids but in different order yield isomers, for example, leucyl-alanine and alanyl-leucine. Natural dipeptides, such as carnosine and anserine, are found in animal tissues. A dipeptide molecule can be hydrolyzed by acids, alkalies, or enzymes (dipeptidases) to yield two amino acids.

References in periodicals archive ?
The generation of amino acids and dipeptides also contributes to the improvement of beef flavor.
Dipeptide pathways, especially those involving glycine and glutamate metabolism, changed significantly across the three time points.
The smallest neutral dipeptide Gly-Gly was retained on the column after derivatisation with AccQ-Tag[TM] and it could be separated from the amino acid glycine, which forms both the amino acid components of this dipeptide.
Human GSS is a homodimer of two 52 kDa subunits that catalyzes the synthesis of glutathione by adding glycine to the dipeptide. GSS gene is located on chromosome 20q11.2 and includes 13 exons (1).
Hermann, "New dipeptide isosteres useful for the inhibition of HIV-1 protease," Bioorganic & Medicinal Chemistry Letters, vol.
When an equimolar amount of complexes 1a-3a was reacted with Ac-L-His-Gly dipeptide, under the abovementioned experimental conditions, no reaction was observed by proton NMR spectroscopy for the complexes 2a and 3a during 48 h.
Gorbitz, "Nanotube formation by hydrophobic dipeptides," Chemistry--A European Journal, vol.
Since SLC15A3 is a late endosome and lysosome-located histidine and dipeptide transporter, we think SLC15A3 may use its transporter function to maintain endosome and lysosome conditions and consequently regulate the activity of DNA and RNA transporters on endolysosomal membrane, thereby affecting cytoplasmic DNA and RNA sensing.
To remedy this shortcoming, an easy and interpretable feature pertaining to the amino acid composition (AAC), dipeptide composition (DPC), and physicochemical property (PCP) were considered.
A part of dipeptide derivatives (5a-c) form six-membered ring compounds (2,5-diketopiperazine: DKP (11) [27]), which may not polymerize anymore.