phenytoin

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Related to diphenylhydantoin: diphenhydramine, phenytoin

phenytoin

[fə′nid·ə·wən]
(pharmacology)
C15H12N2O2 A powder with a melting point of 295-298°C; used as an anticonvulsant and antiepileptic in humans.
References in periodicals archive ?
Phenytoin (diphenylhydantoin, dilantin) has been the chosen anti-convulsive for the treatment of sudden disorders (attack, epilepsy single episode) since the late 30's (Merrit & Putnam, 1938).
On these experimental conditions, diphenylhydantoin 25 mg/kg, body w.
The neurologic hazards of diphenylhydantoin childhood, J Pediatr 1968;73:676-84.
Alcohol Adriamycin Amiodarone Chloramphenicol Cis-platinum Dapsone Diphenylhydantoin Disulfiram (Antabuse) (Dilantin) Glutethimide (Doriden) Gold Hydralazine (Apresoline) Isoniazid (INH) Mega Dose of Vitamin A Mega Dose of Vitamin D Metronidazole (Flagyl) Nitrofurantoin Nitrous Oxide (Furadantin,Macrodantin) (chronic repeated inhalation) Perhexiline (Pexid) Penicillin (Large IV doses only) Pyridoxine (Vitamin B6) Vincristine
The viscachas were quickly sacrificed by intracardiac injection of Euthanyle (0.25 ml/kg body weight, sodium pentobarbital, sodium diphenylhydantoin, Brouwer S.A.).
Postoperatively, he was seizure-free for 6 years under diphenylhydantoin. However, since last year, he started to have uncontrollable laughter attacks as well as contractions originating from the left arm, occasionally spreading through the whole body, lasting approximately 3 min and taking place almost every day.
Use of sodium diphenylhydantoin in treatment of leg ulcers.
Pulmonary capillaritis has been reported as a manifestation of Wegener granulomatosis, microscopic polyangiitis, systemic lupus erythematosus, Goodpasture syndrome, idiopathic pulmonary renal syndrome, Behcet syndrome, Henoch-Schonlein purpura, immunoglobulin A nephropathy, antiphospholipid syndrome, progressive systemic sclerosis, and diphenylhydantoin use.
Some antiepileptic drugs have been implicated in the development of PRCA, including diphenylhydantoin, sodium valproate, and CBZ.
Teratogenic effect of diphenylhydantoin and/or fluphenazine in mice.