Wiberg, "Amber mutants of bacteriophage T4 defective in deoxycytidine diphosphatase
and deoxycytidine triphosphatase on the role of 5-hydroxymethylcytosine in bacteriophage deoxyribonucleic acid," Journal of Biological Chemistry, vol.
ORFs for the 2,3-diacylglucosamine-phosphate biosynthesis UDP-2 and 3-diacylglucosamine diphosphatase
(RWLH04621) were also identified.
Pioneering studies identified inositol glycans generated from Trypanosoma brucei, which displayed insulin mimetic action inhibiting lipolysis, glucose 6 phosphatase, and fructose-1,6 diphosphatase
, well-known insulin-mediated metabolic effects .
The commonest diagnoses were methyl malonic acIdaemia (n=2; 20%), non-ketotic hyperglycinaemia (n=7; 10%), fructose 1,6 diphosphatase
deficiency (n=1; 10%), and biotinidase deficiency (n=1; 10%).
In particular, because phosphorylation of MKK3/6, an upstream enzyme that phosphorylates p38 , was not blocked (Figure 4(c)) and the protein level of phospho-p38 diphosphatase
, MKP-1 , was not enhanced (Figure 4(d)), NGACP treatment seems to directly target MKK3/6, although a specific enzyme assay would be required to obtain better evidence.
The increase in the glycolytic enzyme fructose 1,6 diphosphatase
increases the pentose phosphate pathway.
He demonstrated the first enzyme of the Golgi body (nucleoside diphosphatase
The nucleoside diphosphates are converted to dianionic nucleoside monophosphates (used for the antiporter) and inorganic phosphate by a nucleoside diphosphatase
. It is postulated that inorganic phosphate exits the ER/Golgi lumen via a specific transporter (Fig.