distal convoluted tubule


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Related to distal convoluted tubule: Collecting duct

distal convoluted tubule

[′dist·əl ‚kän·və′lüd·əd ′tü·byül]
(anatomy)
The portion of the nephron in the vertebrate kidney lying between the loop of Henle and the collecting tubules.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive ?
Hypomagnesemia in GS is the consequence of a reduced expression of the epithelial Mg + transport channel TRPM6 in the distal convoluted tubule, which results in decreased magnesium reabsorption (10).
In the present study, histological findings suggest tubular dilatation of both proximal and distal convoluted tubules, in experimental group B, and this is in agreement with the study which reported that human gremlin (GREM1)- overexpressing mice have an increased susceptibility to renal damage, supporting the contribution of gremlin in renal damage progression.
The objective of this study was to evaluate the effects of sodium cyclamate on the kidneys of rat fetuses, in terms of morphometric alterations in the glomerulus, proximal and distal convoluted tubules and collecting duct.
Collector tubules (tc), degenerate collector tubules (dt), epithelial lining of distal convoluted tubules (d), infiltrates (inf), molecular region (mr), proximal convoluted tubules (p), renal glomerulus (rg), and vascular congestion (vc).
It is caused by inability of distal convoluted tubules of the nephron to regulate electrolyte balance owing to mutations, infections, or other causes.
[89] described the fuses kidney rat of age of 7 days consisting of cortex and the medulla, the cortex contain renal corpuscles and renal tubules, cortical rays contain arteries feeding kidney with little connective tissue, each renal corpuscle contain glomerulus and Bowmans Capsule, renal tubules which consist of proximal convoluted tubules contain columnar cells with basal nucleus and of distal convoluted tubules contain cubic cells with circular nucleus.
TRMP6 messenger ribonucleic acid, which is expressed in intestinal epithelial cells and kidney tubules, has a crucial role for transcellular [Mg.sup.2+] absorption from the intestine and from the distal convoluted tubules. Existence of a mutant TRMP6 channel leads to impaired intestinal [Mg.sup.2+] reabsorption and enhanced renal loss (5,6,7,8).
In CIH group, HMGB1 was expressed diffusely in the distended tubular cytoplasms as well as the nuclei of renal tubular epithelial cells, whereas HMGB1 was not or modestly expressed in the nuclei of proximal and distal convoluted tubules in NA group (Figure 3).
(1981) observed degeneration and necrosis of tubular epithelial cells of both proximal and distal convoluted tubules in broiler chicks administered with 95 mg citrinin/kg body weight by crop gavages or mixed with diet.
In hypoplastic fetal and adult kidneys, PAX2 immunoreactivity exhibits less strong nuclear staining in the distal convoluted tubules and parietal epithelial cells of Bowman capsules.
The urinary organs of females consist of a pair of asymmetric kidneys (right and left) constituted by medullar and cortical region with renal corpuscles and proximal and distal convoluted tubules beyond collector tubules.

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