They demonstrated the integration of van der waal heterostructures and reported a large hysteresis effect by constructing graphene-tungsten disulfide
MTPFWRGVSLRPIGASCRDNSECITML CRKNRCFLRSASE; the one is linear type and the other peptide have two disulfide
bonds (C17-C28, C23-C33).
Native thiol and total thiol values were measured using a new method developed by Erel and Neselioglu (17), and disulfide
, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol values were calculated.
Thiols, which include a sulfhydryl (-SH) group, constitute one of the defense systems against unfavorable effects of ROS, and are the main target of ROS, being oxidized by oxidant molecules to form reversible disulfide
A new spectrophotometric technique that was previously described by Erel and Neselioglu  was used to establish thiol/ disulfide
Overweight, obese, and severely obese groups were observed to have significantly elevated native thiol and total thiol ([micro]mol/L, p<0.001) levels than in the normal weight group, while there was also a significant increase in disulfide
([micro]mol/L) levels in the overweight group compared to the normal weight (p<0.01) and obese (p<0.05) groups.
Oxidant sensing by reversible disulfide
A novel, relatively cheap, readily available, and automated assay has been recently described by Erel and Neselioglu, which measures the serum total thiol and native thiol levels and calculates disulfide
concentrations, so that the dynamic thiol/disulfide homeostasis can be determined (7).
Chaitan Khosla, who oversaw the new study, had conducted several studies showing that TG2 can be active or inactive, depending on the forming or breaking of a specific chemical bond, called a disulfide
bond, between two amino acids in the enzyme.
Wilson, "Ascorbate oxidase, protein disulfide
isomerase, ascorbic acid, dehydroascorbic acid and protein levels in developing wheat kernels and their relationship to protein disulfide
bond formation," Cereal Chemistry, vol.
Denaturation and aggregation of muscle proteins during frozen storage are associated with the formation of disulfide
and the interaction of lipid oxidation products with proteins .
Increased levels of plasma LDL, as well as the disruption of this antioxidant system by disulfide
depletion, initiate the atherosclerotic process in the arterial wall.