disulfide bond

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disulfide bond

[dī¦səl‚fīd ′bänd]

(organic chemistry)

References in periodicals archive ?

After RP-HPLC purification, mild oxidative conditions were employed to form the first A-chain intramolecular (A10-A15) disulfide bond, followed by a second purification.

Total chemical synthesis of a heterodimeric interchain bis-lactam-linked peptide: application to an analogue of human insulin-like peptide 3

The bacterial periplasm is an oxidizing environment that facilitates disulfide bond formation for correct protein folding and stability [9, 10].

Top-down characterization of the post-translationally modified intact periplasmic proteome from the bacterium Novosphingobium aromaticivorans

Bacteria often do not form the correct disulfide bonds in recombinantly expressed proteins.

Human complement protein C8: the "Hole" story

Here, the disulfide bonds within the cell, releasing the cargo inside the cell's cytosol within 15 to 30 min.

Nanoinjector does not damage membrane

Molecular modeling studies have suggested four of these cysteines form two disulfide bonds necessary for furin function.

Biochemistry/Molecular Biology. (Abstracts-2003 Annual Meetings)

Tea amino acid residues from the N-terminus end of the 28 kDa protein showed 80 % homology with Excherichia coli thioredoxin, a protein that catalyzes reduction of a disulfide bond or oxidation of a thiol to a disulfide in cytoplasmic proteins.

RESPONSE AND TOLERANCE OF Vibrio cholerae OI TO COLD TEMPERATURES

Effects of disulfide bond reducing agents on sperm chromatin structural integrity and developmental competence of in vitro matured oocytes after intracytoplasmic sperm injection in pigs.

Male Pronuclear Formation and Embryo Development Following Intracytoplasmic Injection of Ovine Pretreated Sperm

Herein, the disulfide bond has the high potential in not only reinforcing the durability during blood circulation but also enabling redox-sensitive release in the intracellular region.

Redox and pH Responsive Poly (Amidoamine) Dendrimer-Heparin Conjugates via Disulfide Linkages for Letrozole Delivery

Ruddock, "Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation," Antioxidants and Redox Signaling, vol.

Synthesis and Experimental Validation of New PDI Inhibitors with Antiproliferative Activity

This material was made by grafting the octadecyl methacrylate and disulfide bond to the PAM.

Structure and Properties of Hydrophobic Aggregation Hydrogel with Chemical Sensitive Switch

Sample CON 8% NPS Ionic bond (%) 1.14 [+ or -] 0.03 0.99 [+ or -] 0.02 Hydrogen bond (%) 1.79 [+ or -] 0.03 2.19 [+ or -] 0.02 Hydrophobic 47.84 [+ or -] 0.04 28.68 [+ or -] 0.00 interaction (%) Disulfide bond (%) 27.62 [+ or -] 0.07 12.27 [+ or -] 0.02 Sample 8% LMPS Ionic bond (%) 0.91 [+ or -] 0.01 Hydrogen bond (%) 2.93 [+ or -] 0.03 Hydrophobic 28.51 [+ or -] 0.05 interaction (%) Disulfide bond (%) 18.47 [+ or -] 0.06 CON (control, i.e., pure surimi gel), NPS (surimi gel with native potato starch), and LMPS (surimi gel with low-moisture potato starch).

Improvement of the Quality of Surimi Products with Overdrying Potato Starches

A key feature of recent mechano-chemistry experiments at the single bond level is that the rate at which the reduction of a protein disulfide bond occurs in the presence of a nucleophile is exponentially dependent on the stretching force.