Sesquiterpenoids and diterpenes
(including the retinoids), and tetraterpenes (carotenoids such as a and a carotene, lutein, lycopene, zeaxanthin and cryptoxanthin) are of the ingredients of H.
Potentiation of methicillin activity against methicillin-resistant Staphylococcus aureus by diterpenes
. FEMS Microbiol Lett 1999; 179: 233-239, doi: 10.1111/j.1574-6968.1999.tb08733.x.
The propolis collected in African and European countries of Mediterranean area also is characterized by its high content of diterpenes
(Graikou et al.
In turn, diterpenes
promote the scavenging of free radicals, which results in the inhibition of lipid peroxidation [46, 47].
Similar to AR inhibitory activities, diterpene
glycosides (17-19) showed no inhibition of AGEs formation and compound 20 showed only slight inhibition, whereas the two coumarins (1 and 2), nine flavonoids (3-11), and five caffeoylquinic acids (12-16) were all more inhibitory than AG ([IC.sub.50] value with 414.77 [+ or -] 5.96 [micro]M).
The use of this natural diterpene
could pave the way towards potential applications to overcome the lack of effectiveness of gentamicin in MRSA strains.
Other marine diterpene
glycosides include eleutherobins and fucosides, which also exhibit notable biologic activity.
prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).
Coffee components called diterpenes
may pitch in against cancer as well.
The mad honey intoxication is a result of so-called GTXs which appear to be a diterpene
derived from polyhydroxylated cyclic hydrocarbon with a 5/7/6/5 ring structure that does not include nitrogen.
Approved as a gel in January of 2012, ingenol mebutate is a natural diterpene
from the Euphorbia peplus flowering plant in Southeast Asia.