Epidemiology and pathophysiology of diverticular disease
. Clin Colon Rectal Surg.
Spectrum of disease and outcome of complicated diverticular disease
. Am J Surg 2003; 186: 696-701.
Neugebauer, "Diagnosis and treatment of diverticular disease
: results of a consensus development conference.
of the colon is a multifactorial disease influenced by ethnicity, diet, and possibly genetics .
These secondary factors are pyloric stenosis, peptic ulcer, appendicitis, ischemic and inflammatory intestinal diseases, diverticular disease
, sigmoid volvulus, obstructive pulmonary diseases, connective tissue diseases, nephrotic syndrome, AIDS, transplantation, the use of some medications (chemotherapeutic agents, steroids, sorbitol, lactulose) various parasitic diseases of the intestine, hematological tumors, and surgical or endoscopic trauma (2).
They noted that CRC among White patients was similar to that seen in western countries with respect to incidence' distribution, sex ratio, and synchronous lesions; in the African population' CRC was uncommon and presented late with advanced disease, with absence of synchronous adenomatous polyps and cancers and absence of diverticular disease
, and was associated with a high fibre and low meat and fat diet.
Diet and risk of diverticular disease
in Oxford cohort of European Prospective Investigation into Cancer and Nutrition (EPIC): prospective study of British vegetarians and non-vegetarians.
While the study makes a renewed case for limiting red meat consumption, increasing fiber consumption is one known preventive measure for diverticular disease
. This step, combined with substituting more servings of red meat with poultry or fish, could help stave off the disorder even if red meat, which is particularly rich in iron, is not entirely phased out of one's diet.
Overall, most patients (80 to 90%) with diverticular disease
While there was gross evidence of sigmoid diverticular disease
, no fistula tract between the intestinal segments was identified.
Consider these tips to promote good colon health and, potentially, reduce your risk of diverticular disease
accounts for 17-40% of the cases of lower GIBs, and results from weakness at the site in the colon wall where the circular muscle layer is penetrated by the vas recta which drape over the dome of the diverticulum and become susceptible to trauma and disruption.