dominant negative mutation


Also found in: Dictionary, Thesaurus, Medical, Legal.

dominant negative mutation

[¦däm·ə·nənt ¦neg·əd·iv myü′tä·shən]
(cell and molecular biology)
Mutation resulting in a gene product that can interfere with the function of the normal gene product in heterozygotes.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
Full browser ?