dynein


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dynein

[dī′nē·ən]
(cell and molecular biology)
A large enzyme complex that hydrolyzes adenosine triphosphate to provide energy to power retrograde [from (+) to (-)] transport along microtubules.
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TEKT2-null sperm has displayed flagellum bend and reduced motility, probably due to disruption of the dynein inner arm [41].
(1) In that case, a 12-month-old boy who presented with such a mucocele and ipsilateral proptosis was found to have an absence of the inner dynein arms linking the microtubule doublets.
The minus end, which directs the motor protein dynein on microtubules, may play a role in transporting the disassembled actin to the periphery of the centrosomes.
Nazio et al., "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy," Journal of Cell Biology, vol.
Similar to TDP-43, FUS is involved in the transport of RNA granules in dendrites [111] using conventional kinesin and dynein as motors [101] and can move into spines in response to glutamate activation [111] through an actin-based motor protein myosin-Va [112].
Lin, "Cyclic AMP inhibits p38 activation via CREB-induced dynein light chain," Molecular and Cellular Biology, vol.
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.
The CpG cg24637308 is located in the body of the Dynein Heavy Chain Domain 1 gene (DNHD1) and is annotated to a CpG island).
However, additional targets in these cells are known to include the molecular chaperone, HSPA2, which facilitates ZP binding, as well as dynein heavy chain, cAMP-dependent protein kinase, alpha-catalytic subunit (PRKACA), and tubulin polymerisation-promoting protein family member 2 (TPPP2), each of which are each important for sperm functionally [175-177].
Axonemal dynein heavy chain 9 (dnah9) is encoded by the DNAH9 gene (Bartoloni et al., 2001).
Cytoplasmic dynein and actin-related protein Arpl are required for normal nuclear distribution in filamentous fungi.