dyskeratosis


Also found in: Medical.

dyskeratosis

[di‚sker·ə′tō·səs]
(medicine)
Imperfect keratinization of individual epidermal cells.
Keratinization of corneal epithelium.
References in periodicals archive ?
Gemahsis' devastated mother Tamar Srondy has told how her young boy was diagnosed with a disease called dyskeratosis congenita - rare and progressive bone marrow failure syndrome.
3) reported a case of Graphium basitruncatum fungemia in a two-year-old child with dyskeratosis congenita who underwent stem cell transplantation two months prior to infection.
Dyskeratosis congenita, palmoplantar keratoderma, lupus erythematosus, dermatomyositis and atopic dermatitis have been associated with PLCA.
Other general features include: Asteatosis (absence of sebaceous glands), normal general mental development, dry skin, nail dystrophy, palmoplantar dyskeratosis, decreased sebaceous and nasal secretions, lack of dermal ridges, and fragile-appearing skin.
Dyskeratosis congenita or Zinsser-Cole-Engman syn-dromeis is a rare inherited bone marrow failure syndrome (IBMFS) characterized by diagnostic triad of reticulated skin hyperpigmentation, nail dystrophy, and oromucosal leukoplakia (1).
A telomerase component is defective in the human disease dyskeratosis congenita.
On the other hand studies were done on dyskeratosis congenital and ataxia telangiectasia and it was found that these patients did not show atherosclerosis.
An extensive variety of cutaneous conditions bearing a resemblance to CARP were considered in the differential diagnosis, including acanthosis nigricans (AN), tinea versicolor, Darier disease, terra firma-forme dermatosis, prurigo pigmentosa, flagellate dermatosis, and dyskeratosis congenita.
There was hypogranulosis or agranulosis in subcornoid lamella region along with mild dyskeratosis and a few vacuolar cells.
Dyskeratosis and a suprabasal cleft may be seen, creating a so-called "dilapidated brick wall" appearance (figure 2), with dyskeratosis identified in the form of corp ronds and grains.
Oral squamous cell carcinoma in a case of dyskeratosis congenita.
W, Telomerase RNA structure and function : impkications for dyskeratosis congenital, Trends Biochem Sci.