dyspareunia


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dyspareunia

[‚dis·pə′rün·ē·ə]
(medicine)
The occurrence of pain during sexual intercourse.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Two innovative, nonestrogen therapies--ospemifene and prasterone--have been approved for the treatment of dyspareunia associated with VVA.
In two primary 12-week placebo-controlled efficacy trials, the women taking Intrarosa experienced a significant reduction in symptoms of dyspareunia, as well as significant improvements in the percentage of vaginal superficial cells and parabasal cells, as well as vaginal pH, concluded the company.
Portman and his colleagues assessed the efficacy, safety and tolerability of ospemifene for women with moderate to severe vaginal dryness or moderate to severe dyspareunia.
"Lasofoxifene improved both objective signs and self-reported symptoms associated with vaginal atrophy, including dyspareunia," which 40% of the study participants had identified as their most common and bothersome vaginal symptom when the study began, principal investigator James Simon, M.D., reported at the annual meeting of the American College of Obstetricians and Gynecologists.
(10) In comparison, women are more likely to cite the consequences of hormonal insufficiency (VVA, dyspareunia) and lack of a partner as the most important determinants of their postmenopausal sexual functioning.
The results demonstrated statistically significant and clinically meaningful improvements in dyspareunia, a co-primary endpoint, and vaginal dryness, a secondary endpoint, stated the company.
His observations led him to conclude that the dyspareunia many postmenopausal women experience has more to do with introital stenosis than vaginal dryness.
GSM often includes genital symptoms of vaginal dryness, burning, and irritation; adverse effects on sexual function (lack of lubrication, dyspareunia, decreased libido); and urinary symptoms of urgency, dysuria, and recurrent urinary tract infection (UTI).
MAY-44, which was acquired by Mayfield in February, will be developed through the 505(b)(2) clinical pathway for the treatment of dyspareunia in pre and post-menopausal women.
Collectively, for studies included in this review that specifically reported the rate of dyspareunia before and after surgery, 47% of women reported improvement in dyspareunia; 39% reported no change; 18% reported deterioration in dyspareunia; and only 4% had de novo dyspareunia.
This was not a sufficient benefit considering the potential adverse events that include mesh exposure, and the pelvic pain and dyspareunia associated with using these products.
Other studies found that decreased levels of estrogen lower a woman's sex drive, cause vulvovaginal atrophy and dryness, and decrease clitoral blood flow, largely associated with dyspareunia. The risk for HSDD is greatest in women who have undergone surgical menopause.