The probable mechanism is the direct cytotoxic effect on the eccrine glands
of folinic acid, fluorouracil, and oxaliplatin, but more observations are needed to confirm this hypothesis.
are found throughout the skin, but are especially concentrated in palms of hands, soles of feet, and the forehead.
are present throughout the skin but are most abundant in the palms, soles, axilla, eyelid margins and in the surface dermis.
When your body heats up, eccrine glands
release sweat that cools your body.
Hidradenocarcinoma originates in the eccrine glands
located in sun-exposed areas and accounts for approximately 6% of malignant eccrine tumors and <0.001% of all skin cancers.[sup], Hidradenocarcinoma usually presents as a solitary, firm, asymptomatic intradermal nodule measuring 1–5 cm, covered by intact or occasionally ulcerated purple-, pink-, or blue-colored lesions.[sup] While hidradenocarcinoma typically grows slowly over many years, it may suddenly undergo a rapid increase in size.
are found all over the body, with the highest density in palms and souls.
See a doctor if: *You suddenly begin to sweat much more or less than usual *Sweating disrupts your daily routine *You experience night sweats for no apparent reason *You notice a change in your body odour Your skin has two main types of sweat glands: eccrine glands
and apocrine glands.
Skin adnexal tumors (SATs) are those neoplasms that differentiate toward or arise from pilosebaceous unit, eccrine sweat glands or apocrine sweat glands, and these tumors are classified into four groups that exhibit histologic features analogous to hair follicles, sebaceous glands, and eccrine glands
.  These tumors are derived from multipotential undifferentiated cells present within the epidermis or its appendageal structures and the histologic features of a tumor are related to the activation of molecular pathways responsible for forming the mature adnexal structure.
There are more eccrine glands
on, hands and feet than elsewhere, which may explain why these areas are often affected by hyperhidrosis.
INTRODUCTION: Acrospiroma is an uncommon adnexal tumor arising from eccrine glands
and commonly seen on the face and the upper extremities.
The eccrine glands
are sweat glands that are not connected to hair follicles.
A bad case of smelly feet can come from the eccrine glands
on the soles of vour feet.