Charteris, "Prevalence of ectopia lentis
and retinal detachment in Marfan syndrome," Acta Ophthalmologica, vol.
The frequency increases to 8-38% in the presence of "ectopia lentis
" (13, 14).
Different surgical techniques for the management of ectopia lentis
have been reported such as lensectomy and anterior chamber IOL implantation, open loop3,4 or scleral fixation of IOL implant(SF-IOL).5 However, the risks include iritis, pigment dispersion, corec-topia, glaucoma, corneal endothelial loss, and retinal detachment.
Cardinal features of the disorder include tall stature, ectopia lentis
, mitral-valve prolapsed, aortic-root dilatation, and aortic dissection (Collod-Beroud and Boileau, 2002).
Differential diagnoses of ectopia lentis
also include trauma, syphilis, sulfite oxidase deficiency, and Weill--Marchesani syndrome.
* More weight is given to aortic root aneurysm / dissection and ectopia lentis
. "In the absence of findings that are not expected in [Marfan syndrome], the combination of ectopia lentis
and aortic root enlargement/dissection should be sufficient to make the diagnosis," the authors wrote, noting that all other cardiovascular and ocular manifestations of the condition, as well as findings in the skeleton, dura, skin, and lungs, "contribute to a systemic score that guides diagnosis when aortic disease is present but ectopia lentis
Identification of FBN1 gene mutations in patients with ectopia lentis
and marfanoid habitus.
By that time, other organ systems were known to be involved, as revealed by congenital displacement of the lens (ectopia lentis
) and mitral valve disorders.
Homocystinuria causes mental retardation ectopia lentis
osteoporosis, and thromboembolism.
One case is that of ectopia lentis
as the result of familial traits alone, without involvement of other systems.
This study was undertaken to evaluate the refractive outcome and complication profile of sutureless, glueless, flapless, intrascleral fixation of PCIOLs in pediatric patient presenting with congenital ectopia lentis
These included microcornea (2%), microcornea with iris coloboma (1%), sclerocornea (0.5%), iris coloboma (7%), aniridia (6.5%), ectopia lentis
(4%), coloboma of lens (1%), anophthalmos (0.5%) and microphthalmos (1.5%).