The probes were also able to detect ectromelia
virus but with a lower sensitivity (data not shown).
The pathogenesis of the acute exanthems; an interpretation based on experimental investigations with mousepox; infectious ectromelia
The Attenuated Vaccinia-Lister Vaccine LC16m8 Protects Mice from Aerosolized Ectromelia
A panel of 15 lyophilized plasma samples to which gamma-irradiated, heat-inactivated orthopox viruses (MPV, CPV, VAC, CML, and ectromelia virus) had been added was provided by the European Network for the Diagnosis of Imported Viral Diseases (ENIVD; Berlin, Germany).
6] copies/mL of ectromelia virus, a nonpathogenic orthopox virus for which our test had not been designed.
The formation of A-type inclusion bodies is restricted to cells infected with CPXV, ectromelia
virus, and raccoonpox virus.
15) reported symmetrical hind-limb ectromelia
and ectrodactyly after R.
Today, technology allows genetic engineering of potentially devastating agents such as modified ectromelia
virus (2), the weaponizing variola virus (former USSR) (3), the long distance dispersal of yellow fever-infested mosquitos (United States) (4), and the weaponizing of anthrax spores by many nations.
Most malformations (47%) involved ectromelia (absence of all or part of a limb), ectrodactyly (absence of all or part of a digit) of the hindlimb, or asymmetrical development of hindlimbs (Figure 2, Table 2).
The principle lesions were ectromelia and ectrodactyly involving hindlimbs, although occassionally missing forelimbs and eyes were also noted.
Although the formation of typical A-type inclusions is restricted to cells infected with cowpox virus, ectromelia
virus, and raccoonpox virus (2), the sequence coding the N-terminus of the protein is highly conserved in many viruses, including CPXV, VACV, variola virus, camelpox virus, and ectromelia
LC16m8 Protects Mice Against Aerosolized Ectromelia