Death of the heart muscle, in turn, causes chest pain and electrical instability
of the heart muscle tissue.
PCI is indicated immediately when fibrinolysis has failed <50% ST segment resolution at 60-90 minutes or at any time in the presence of haemodynamic or electrical instability
or worsening ischemia.
The principal factor in the prevention of electrical instability
is correct ICD programming.2,3, A patient with ES has to be hospitalized and monitored in an intensive care unit.
A prolongation of the QT interval is associated with an increased rate of cardiovascular morbidity and mortality related to electrical instability
and risk of ventricular arrhythmogenesis.
They are regarded as markers of electrical instability
that predispose to ventricular arrhythmia.
Otherwise, all remaining muscles showed no evidence of electrical instability
or conductive disorders.
When a trigger can be identified, its correction may reverse the electrical instability
of the myocardium.
Recent evidences suggest that asymmetric brain activity during acute emotional stress causes asymmetric activation of heart leading to production of inhomogeneous areas of repolarization and production of electrical instability
As a result, there is an abnormal increase in the firing rate at sympathetic nerve endings thus leading to electrical instability
by decreasing heart rate variability consequently generating potentially lethal ventricular tachyarrhythmias.
Here we show that inhibition of the endogenous enzyme aldose reductase (ALR2) activity by the newly synthetized benzofuroxane derivative 5(6)-(benzo[d]thiazol-2-ylmethoxy)benzofuroxane (BF-5m) results in cardioprotection from the electrical instability
and increased vasomotor tone caused by high levels of glucose into the heart.
Winfree, "Electrical instability
in cardiac muscle: phase singularities and rotors," Journal of Theoretical Biology, vol.
However, when this effect is confined to a limited area of the heart, segmental delays in myocardial repolarization may produce global cardiac electrical instability