A DNA-electrochemical biosensor is a sensing device composed of a DNA layer (the biological recognition element) immobilized on the electrode surface (the electrochemical transducer), to detect target analytes that interact with DNA at nanoscale.
The recent advances on the characterization of the G-rich DNA sequences, at the surface of electrochemical transducers, and the design and applications of GQ electrochemical biosensors for the detection of metal ions, GQ ligands, and other small organic molecules, proteins, and cells will be presented.
Understanding the redox behaviour and adsorption process of the DNA probe at electrochemical transducers is critical for the design and successful application of DNA-electrochemical biosensors [2-7, 9-11, 38-46].
The electrical dependency is eliminated by coupling the biosensor to an electrochemical transducer
that is capable of autonomous energy production, the fuel cell.
offers several advantages, such as high sensitivity, simplicity, inexpensiveness, and accurate specificity for converting DNA hybridization results into useful analytical signals [18-21].
The second class of chemosensors depends on reversible electrochemical transducers
to achieve the chelation of ions in a chemical reversible manner.
Gohier et al., "Carbon nanowalls as material for electrochemical transducers
," Applied Physics Letters, vol.
based on surfactant bilayers for the direct detection of affinity interactions.
(3.) Leclere, M., 'Optical and Electrochemical Transducers
Based on Functionalized Conjugated Polymers', Adv.
Following an introductory chapter, the remaining nine carry titles: Basic electrochemical principles; Electrochemical transducers
in biology and medicine; Enzyme-based electrochemical biosensors; Fabrication and miniaturization techniques; Optical technology; Miscellaneous transducer technologies; Immunosensors; 'Living' biosensors; and Future directions.