electrophilic


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electrophilic

[i¦lek·trō′fil·ik]
(physical chemistry)
Pertaining to any chemical process in which electrons are acquired from or shared with other molecules or ions.
Referring to an electron-deficient species.
References in periodicals archive ?
In contrast to halogen-bonds, chalcogen-bonds feature two substituents on the interacting atom as well as two electrophilic axes.
Recently, we described the preparation of novel polyfaryl ether ketone)s containing amide linkages in main chains by the electrophilic Friedel-Crafts acylation copolycondensation, the resulting copolymers with low content of amide linkages had not only much higher [T.
Irreversible cell damage can occur by electrophilic radicals that can react with oxygen giving rise to reactive oxygen species.
They can metabolize insecticides by facilitating their reductive dehydrochlorination or by conjugating glutathione to xenobiotic compounds with electrophilic centers (e.
Another reported approach to cyclopropyl generation is the addition of bromonitromethane to electrophilic alkenes to yield nitrocyclopropyls.
Among their topics are the role of reactive metabolites in genotoxicity, the bioactivation and inactivation of cytochrome P450 and other drug-metabolizing enzymes, intrinsically electrophilic compounds as a liability in drug discovery, the retrospective analysis of structure-toxicity relationships of drugs, experimental approaches to detecting reactive metabolites, structural alert and reactive metabolite analysis for the top 200 drugs in the US market by prescription, and mitigating toxicity risks with affinity labeling drug candidates.
CH2O (FA) is a highly reactive substance due to its strong electrophilic properties, and it can change from a solid or liquid into the gaseous form at room temperature.
Glycidyl methacrylate (GMA) is a bifunctional monomer containing an unsaturated group together with a highly electrophilic epoxide moiety.
hippuric acid-histidine-leucine), whereby the carbonyl group becomes polarized and is subjected to an electrophilic attack.
A substantial chapter follows on the wide range of reagents and methods of aromatic nitration, covering the areas of acid-catalyzed electrophilic nitration, homolytic nitration, and nucleophilic nitration.
On the interaction between glyceraldehyde-3-phosphate dehydrogenase and airborne particles: evidence for electrophilic species.
A more recent interesting application of superacids has been the preparation of stable solutions and crystalline salts of a variety of novel cations of non metallic elements that are too highly electrophilic to be obtained in aqueous media.