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Related to electrophoresis: Protein electrophoresis, Hemoglobin electrophoresis


(ĭlĕk'trōfərē`sĭs): see colloidcolloid
[Gr.,=gluelike], a mixture in which one substance is divided into minute particles (called colloidal particles) and dispersed throughout a second substance. The mixture is also called a colloidal system, colloidal solution, or colloidal dispersion.
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(also cataphoresis), the migration of colloidal particles or ionized macromolecules under the influence of an external electric field. Electrophoresis was discovered by F. F. Reuss in 1807; it is regarded as the most important electrokinetic phenomenon. An approximate relation between the velocity v of the moving particles and the electric field strength E is given by Smoluchowski’s equation:

where η is the viscosity of the medium, D is the dielectric constant, and £ is the electrokinetic potential.

Electrophoresis is used in electrochemistry to study the electric double layer and ion adsorption on a surface; it also has medical applications. In industry it is used to isolate natural rubber from latex, purify water, and separate kaolin from sand. It is used in biochemistry to analyze, separate, and purify biopolymers (chiefly proteins), bacterial cells, viruses, amino acids, and vitamins.

The practical application of electrophoresis began after the Swedish scientist A. Tiselius designed a special apparatus for the moving-boundary electrophoresis of proteins in solution (1937). Electrophoretic methods involving the use of inert carriers, such as paper and gels, have gained the widest application. They have been given the general designation of zone electrophoresis because fractions of the separate substances form separate immiscible zones in the carrier. Electrophoresis is frequently combined with other methods of separating organic compounds, for example, with chromatography. A technique has been developed for concentrating the electrophoretic zones of biopolymers in gels, which increases the resolving power of the method (disk electrophoresis). The combining of the antigen-antibody reaction with electrophoresis was the basis for the creation of immunoelectrophoresis. Electrophoretic analysis of biological fluids, such as blood serum (used primarily to study proteins), is widely used in the diagnosis of many diseases.


Larskii, E. G. Melody zonal’nogo elektroforeza. Moscow, 1971.
Dukhin, S. S., and B. V. Deriagin. Elektroforez. Moscow, 1976.



(physical chemistry)
An electrochemical process in which colloidal particles or macromolecules with a net electric charge migrate in a solution under the influence of an electric current. Also known as cataphoresis.


The science of objects moving in a fluid when an electric charge is applied. Electrophoresis is the basis of E Ink's electronic paper display technology (see E Ink).
References in periodicals archive ?
The electrophoresis market witnessed healthy growth during the last decade owing to the rising aging population, rising R&D expenditure, and international research collaborations.
According to data collected in the year 2012, the market leaders of electrophoresis equipment and accessories market were the US, enjoying a market share of 39.
The Agilent 2100 bioanalyzer includes support for on-chip flow cytometry, 21CFR part 11 compliance and electrophoresis assays.
Also, the joint research group has successfully reduced in size the new system to a quarter the conventional 2-D electrophoresis system.
Laboratory investigation of a multistate food-borne outbreak of Escherichia coli O157:H7 by using pulsed-field gel electrophoresis and phage typing.
Possibilities of performing electrophoresis in capillaries were investigated by Hjerten [4], Everaerts [5], and Virtanen [6] but their work did not attract much attention to capillary electrophoresis (CE).
PE Biosystems' electrophoresis systems serve a wide spectrum of researchers ranging from those working in small laboratories to those in production-scale genomics facilities.
Capillary electrophoresis is performed using capillaries 50um - 100um in internal diameter and 30cm - 100cm in length.
Owl Separation, Sebia, SERVA Electrophoresis GmbH, and Thermo Fisher Scientific Inc.
Announcement of competition: Equipment for capillary electrophoresis and associated consumables.
com has added a new market research report: Global Electrophoresis Equipment and Supplies Industry https://www.

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