emodin


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Related to emodin: frangula emodin

emodin

[′em·ə·dən]
(organic chemistry)
C14H4O2(OH)3CH3 Orange needles crystallizing from alcohol solution, melting point 256-257°C, practically insoluble in water, soluble in alcohol and aqueous alkali hydroxide solutions, occurs as the rhamnoside in plants such as rhubarb root and alder buckthorn; used as a laxative.
References in periodicals archive ?
The research revealed for the first time that emodin is a potent selective inhibitor of 11E--HSD1, and as a result it effectively limits the effect of the glucocorticoids, and ameliorates diabetes and insulin resistance.
The compounds used in this study were purchased from Sigma-Aldrich (Milwaukee, WI) and include chrysin (purity > 97%), phloretin (> 95%), kaempferol (> 95%), galangin (95%), naringenin (95%), genistein (98%), quercetin (99%), myricetin (95%), cantharidin (98%), luteolin (> 90%), baicalein (98%), daidzein (> 95%), emodin (> 90%), apigenin (> 90%), and diosmin (95%).
Recently, chemically modified emodin derivatives were shown to induce cell cycle arrest, caspase dependent cell death and DNS binding interaction (Narender et al.
Aloe emodin has been shown to inhibit lipid peroxidation [11].
Emodin (1) is the major bioactive compound of several herb species, which belongs to anthraquinone class of compound.
Indeed, various anthraquinones isolated from plants, such as rhein, aloe-emodin and emodin, have been reported to possess antiangiogenic activity in both in vitro and in vivo assays (Cardenas et al.
2010, Emodin, a natural product, selectively inhibits 11 beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.
have isolated the endophytic fungus designated INFU/Hp/KF/34B and later identified as Thielavia subthermophila from Hypericum perforatum and studied the production of hypericin, a naphthodianthrone derivative, and its precursor, emodin (Kusari et al.
Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
Pure compounds rhein, aloe-emodin and emodin were obtained from National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China).