Suppression of lipopolysaccharide-induced upregulation of toll-like receptor 4 by
emodin in mouse proximal tubular epithelial cells.
The reference compounds AloeEmodin, Rhein,
Emodin, Chrysophanol, Physcion were purchased from the National Institute for Control of Pharmaceuticals and Biological Products (Beijing, China), and Sennoside A and Sennoside B from the Mansite Pharmaceutical Co.
2016)
Emodin ameliorates acute lung injury induced by severe acute pancreatitis through the up-regulated expressions of AQP1 and AQP5 in lung.
Emodin, an anthraquinone derivative from Rheum officinale Baill, enhances cutaneous wound healing in rats.
The constituents of the rhubarb extract include anthraquinones (
emodin, chrysophanol, rheni, physcion, aloe-
emodin, and the glycosides of these substances); anthrone; dianthrones (dianthrones of chrysophanol,
emodin, aloe-
emodin, and glucorhein); heterodianthrones (palmidins A and B); tannins (glucogallin and gallic acid); and starch and calcium oxalate [16, 17].
Emodin is toxic to amphibian embryos and can stop hatching.
Emodin were found only in the ethanol extracts of leaf and it is absent in the all the stem extracts.
Emodin, a natural product, selectively inhibits 11 beta- hydroxysteroid dehydrogenase type I and ameliorates metabolic disorder in diet - induced obese mice.
It uses pure nature-identical trans-resveratrol that is free from pesticides and
emodin, a potential concern with other forms of resveratrol.
An experiment was conducted to determine the concentration of
emodin, the main bioactive content of aqueous extracts of Sargentodoxa cuneata (SC).
Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with
emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3.
The anti-inflammatory effect of Hp is attributed by Bezakova et al (1999) to its isolated constitutes anthrone, anthroquinone,
emodin hypericin and pseudohypericin while its analgesic effect may be attributed to the presence of flavonoids, tannins and saponins (Sanchez-Mateo 2006, Bezakova 1999).
