Hernandez, "Enamel organ
proteins as targets for antibodies in celiac disease: implications for oral health," European Journal of Oral Sciences, vol.
defective desmosomes) or, more likely to the intrinsic production of proteinases, enzymes that normally degrade the central zone of enamel organ
after tooth development.
INTRODUCTION: Ameloblastomas are benign locally aggressive, polymorphic neoplasms of proliferating odontogenic epithelial origin, arising from cell rests of enamel organ
, either remnants of dental lamina or remnants of Hertwig's sheaths, the epithelial rest of Malassez, the developing enamel organ
, basal cell epithelium of the jaws.
The enamel is produced by ameloblasts (Figure 2D) originated from the inner epithelium of the enamel organ
, which is originated from the dental lamina.
The researchers said that after 3 weeks the cells bundle started to look like a tooth, containing dental pulp, dentin, enamel space and enamel organ
, the BBC reported.
The researchers said that after three weeks the bundle of cells started to resemble a tooth: "The tooth-like structure contained dental pulp, dentin, enamel space and enamel organ
." However, the "teeth" were not as hard as natural teeth.
An odontogenic cyst is formed by activation of odontogenic cell rests entrapped within the bone tissue or gingival tissue of the jaws, such as the epithelial remains of Malassez, the dental lamina (cell rests of Serres), or the enamel organ
. Inflammatory odontogenic cysts are formed due to activation of these cell rests by an inflammatory process.
The literature mentions several hypotheses for the etiology of regional odontodysplasia such as trauma, local ischemia, viral infection, vascular defect, irradiation, vitamin deficiency, metabolic and nutritional disorders, Rh incompatibility, local somatic mutation, hyperpyrexia, manifestation of latent virus in the odontogenic epithelium during dental development, genetic mutation of odontoblasts, premature degeneration of the enamel organ
, and idiopathic factors (ALEVA et al., 1996; NEUPERT; WRIGHT, 1989; REZENDE et al., 1998; VOLPATO et al., 2008).