MRI Brain Findings###Cystic
encephalomalacia.###Bilateral periventricular and subependymal###Polymicrogyria in the frontal lobes,###Normal
In our patient, the
encephalomalacia did not include dopaminergic regions (nigrostriatal).
Cerebellar folia were globally attenuated with a focally extensive focus of
encephalomalacia (Fig 4A).
Secondary lesions were detected in cases with corpus callosum abnormality, atrophy,
encephalomalacia and hydrocephaly.
(b) MRI at day 4 of life shows cystic
encephalomalacia of the bilateral frontal and left parietal lobes and artifact consistent with a previous intraventricular hemorrhage, hemorrhagic contusion, and subdural hematoma.
The patient presents with an extensive area of
encephalomalacia within the left cerebral hemisphere involving the temporal and frontoparietal lobes with volume loss.
MRI of the brain showed abnormal results (prominent white matter disease and focal
encephalomalacia).
All other CT findings were defined as nonsignificant (patients with chronic pathologic CT findings such as chronic brain infarction,
encephalomalacia, vasculopathy or gliosis).
A second MRI performed 4 months after the first revealed gliosis and
encephalomalacia in the thalami and basal ganglia bilaterally, with volume loss and evidence of early mineralization in the left basal ganglia.
The computed tomography scan (CT scan) of brain performed before pregnancy showed multiple parenchymal/perinuclear subependymal calcification, focal
encephalomalacia. Echocardiography (ECHO) revealed a small patent ductus arteriosus (PDA) of 2 mm with left to right shunt.
Stigmata of old TBI on an MRI also include areas of
encephalomalacia and gliosis, particularly in areas prone to coup-contrecoup forces, such as the frontal lobe (anterior as well as inferior margin along the cribiform plate), anterior temporal lobe, and the occipital pole.
MRI revealed areas of chronic infarcts with associated early
encephalomalacia changes and gliosis in left frontal region and left basal ganglia (fig-1).