Encephalopathy

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Related to encephalopathies: alcoholic encephalopathy

encephalopathy

[en‚sef·ə′läp·ə·thē]
(medicine)
Any disease of the brain.

Encephalopathy

 

a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
Toxic and metabolic encephalopathies may range in severity from the acute confusional state to frank coma," McCoyd added.
Atypical bovine spongiform encephalopathies, France, 2001-2007.
Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases).
In this chapter, he details research showing that knockout animals for the normal prion protein are not able to develop spongiform encephalopathies when inoculated.
Eating meat contaminated with infectious prions is only one way that spongiform encephalopathies are transmitted.
CJD belongs to a family of rare disorders in humans and animals called transmissible spongiform encephalopathies, or TSEs: "encephalopathies" because they're diseases of the brain, "spongiform" because they leave infected brain tissue looking spongy, and "transmissible" because they can be spread, though not easily.
Until now, there has been no way to accurately diagnosis these diseases - collectively known as transmissible spongiform encephalopathies - in the living.
According to the Food and Drug Administration's Center for Food Safety & Nutrition, prions are associated with a group of diseases called Transmissible Spongiform Encephalopathies (TSEs).
16, 2015 /PRNewswire/ -- Turing Pharmaceuticals AG, a privately-held biopharmaceutical company focused on developing and commercializing innovative treatments for serious diseases and conditions, today announced dosing of the first group of subjects in the TUR-004 single ascending dose study, the first clinical study in a comprehensive program aimed at obtaining approval for the treatment of epileptic encephalopathies.
10/2014 for the supply of integrated rapid test system for examining brain about 27,000 samples a year (for a period of 1 + 1 year) for the monitoring of bovine spongiform encephalopathy (BSE) and Transmissible Spongiform Encephalopathies (TSEs) of sheep and goats, as well as all necessary equipment and consumables for conducting the tests.
Coverage begins with human brain development and proceeds through neurological evaluation, hypoxic-ischemic encephalopathy, intracranial hemorrhage, metabolic encephalopathies, disorders of the motor system, intracranial infections, perinatal trauma, intracranial mass lesions, and drugs and the developing nervous system.