Rettie, "CYP4B1: an enigmatic P450 at the interface between xenobiotic and endobiotic
metabolism," Drug Metabolism Reviews, vol.
Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic
Role of human aldehyde dehydrogenases in endobiotic
and xenobiotic metabolism.
The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic
Glutathione S-Transferases (GSTs, EC.22.214.171.124) are a superfamily of multifunctional enzymes that detoxify endobiotic
and xenobiotic compounds by conjugating glutathione (GSH) to a hydrophobic substrate.
In addition, BCRP, like P-gp, is also expressed in normal tissues such as liver hepatocytes, the apical membrane of the epithelium in the intestine, the ducts and lobules of the breast, the luminary surface of brain capillaries, and the human placenta (Malie-paard et al., 2001) and it plays an important role in the disposition of endobiotic
and xenobiotic compounds, protecting the body or certain tissues from exposure to toxic substrates (Jonker et al., 2002).
bacteria associated with Pyrsonympha vertens, a symbiotic protozoon of the termite Reticulitermes flavipes.
This is the first evidence indicating that an endobiotic
autotrophic organism may parasitize its animal host.
Caron et al., "Regulation of endobiotics
glucuronidation by ligand-activated transcription factors: Physiological function and therapeutic potential," Drug Metabolism Reviews, vol.