endochondral ossification


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endochondral ossification

[¦en·dō′kän·drəl ‚äs·ə·fə′kā·shən]
(physiology)
The conversion of cartilage into bone. Also known as intracartilaginous ossification.
References in periodicals archive ?
1994) who, when evaluating the effects of LIPUS on endochondral ossification observed an increase in ZP, with no change in ZH, in metatarsal cultures of mice of 16 and 17 days of age lifetime.
sup][9],[10],[11],[12],[13] Other important genes and transcription factors involved in signaling pathways related to selected endochondral ossification included the following: DKK1 in the Wnt signaling pathway; BMP6 , BMP4 , and BMP2 in the BMP signaling pathway; DMP1 and MGP in the matrix mineralization pathway; IHH in the hedgehog signaling pathway; and RUNX2 - and SRY-related high mobility group-box gene 9 in transcription factors related to ossification.
This important and unique study provides new detailed postnatal developmental histological anatomy description of the ossification centres of the acromial and sternal ends of the human clavicle, and its differences from regular long bone endochondral ossification.
Endochondral ossification predominates over intramembranous ossification in this region.
In the first phase, growth rate of antler skin is faster than that of endochondral ossification; while, in the second phase, endochondral ossification rate is faster, and then antler skin begins to drop to form bone antler.
It is named chondrocranium since most of its bones are made up of cartilage and ossify by the process of endochondral ossification [1].
Dysplasia of endochondral ossification, affecting secondary spongiosa, are characterized by errors in resorption or remodeling of secondary spongiosa, which results in focal densities and/or striations within the trabecular bone (3).
We conclude that Pb delays fracture healing at environmentally relevant doses and induces fibrous nonunions at higher doses by inhibiting the progression of endochondral ossification.
This abnormal pattern of cartilage matrix assembly explains well the abnormalities in endochondral ossification leading to shortness and deformity of the skeletal segments.