occurs at the medial border and lateral angle of the scapula, where OC commonly develops.
: how cartilage is converted into bone in the developing skeleton.
The stimulation promoted cell histodifferentiation and proliferation, initiating the cascade of endochondral ossification
Some studies suggested that AA, a classic n-6 PUFA, has been reported to inhibit endochondral ossification
and bone mineralization through activating inflammatory factors like PGE-2 and LTs [20, 21].
Effect of alendronate on endochondral ossification
in mandibular condyles of growing rats.
In the present study, we focused on the tissue-specific distribution of the TPD52 and TPD54 in bone and cartilage tissue in vivo and the cell-specific physiological roles of those proteins on proliferation and differentiation of chondrocytes in endochondral ossification
[sup],,,, Other important genes and transcription factors involved in signaling pathways related to selected endochondral ossification
included the following: DKK1 in the Wnt signaling pathway; BMP6 , BMP4 , and BMP2 in the BMP signaling pathway; DMP1 and MGP in the matrix mineralization pathway; IHH in the hedgehog signaling pathway; and RUNX2 - and SRY-related high mobility group-box gene 9 in transcription factors related to ossification.
At week 1 post-fracture, in the control group, moderate staining for BMP-2 was seen in osteogenic cells, fibroblast-like cells or chondrocytes, osteoblasts in the subperiosteal bone, proliferating chondrocytes and osteoblasts in the trabecular bone near the endochondral ossification
HOA1 (hydroxyacid oxidase 1) on 20p12.3, RSPO2 (R-spondin 2) on 8q23.1 and CCDC91 (coiled-coil domain containing 91) 12p11.22 are implicated in the endochondral ossification
Theories such as aberrant joint loading and issues with epiphyseal endochondral ossification
have also been suggested to contribute to the proposed multifaceted etiology of JOCD of the knee.
of retained fetal bones is the most widely accepted aetiological hypothesis.