For this reason, the Tier 1 screening assays can be interpreted in endocrine toxicity
pathways rather than in AOPs because these assays are not designed to measure long-term adverse responses in individuals or in populations.
Soy baby formula contains isoflavones, which according to ADM documents, have the potential for chronic endocrine toxicity
Grade II-IV endocrine toxicity
was reported in 24% of the chemotherapy-alone arm and 48% of the goserelin arm (P = .
However, Rozerem is associated with "numerous risks, including potential endocrine toxicity
," regulators asserted.
The graph implies that the product has no toxicity risk, regulators assert, adding that the implication is particularly troubling because Rozerem is associated with "numerous risks, including potential endocrine toxicity
Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process - including the areas of mutagenicity, carcinogenicity, endocrine toxicity
, organ-specific toxicity, population monitoring, and ecotoxicology.
Tributyltin synergizes with 20-hydroxyecdysone to produce endocrine toxicity
The authors aim to enable chemists to assess endocrine toxicity
early in the design process when they are first developing new molecules, long before chemicals reach market.
None of the animal experiments showing low-dose endocrine toxicity
from bisphenol A, however, have been replicated (Ashby J.
Body distribution and endocrine toxicity
of hexachlorobenzene (HCB) in the female rat.