endogenous pyrogen


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endogenous pyrogen

[en′däj·ə·nəs ′pī·rə·jən]
(biochemistry)
A fever-inducing substance (protein) produced by cells of the host body, such as leukocytes and macrophages.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Fever occurs in response to a challenge with endotoxins via the release of endogenous pyrogens by systemic mononuclear phagocytes (Blatteis & Sehic, 2000).
Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed.
Upon recognition of these exogenous pyrogens, endogenous mediators, also known as endogenous pyrogens, engage the febrile system.