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Related to endometriosis: endometrial cancer


(ĕn'dəmē'trē-ō`sĭs), a condition in which small pieces of the endometrium (the lining of the uterusuterus,
in most female mammals, hollow muscular organ in which the fetus develops and from which it is delivered at the end of pregnancy. The human uterus is pear-shaped and about 3 in. (7.
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) migrate to other places in the pelvic area. The endometrial fragments may move to the fallopian tubesfallopian tube
, either of a pair of tubes extending from the uterus to the paired ovaries in the human female, also called oviducts, technically known as the uterine tube.
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, ovaries, or other pelvic structures (e.g., the bladder or rectum). The migrated tissue retains its character and changes with the fluctuations of the menstrual cycle, bleeding at the time of menstruationmenstruation,
periodic flow of blood and cells from the lining of the uterus in humans and most other primates, occurring about every 28 days in women. Menstruation commences at puberty (usually between age 10 and 17).
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. The blood becomes trapped in cysts that can grow from the size of a pinhead to the size of a grapefruit. Symptoms of endometriosis can be absent or can include painful menstruation, severe abdominal or low back pain, painful intercourse, and rectal bleeding at the time of menstruation. Symptoms often disappear with pregnancy, but 30%–40% of women who have endometriosis are infertile.

The cause of endometriosis is unknown. One hypothesis is that the endometrial fragments move back up through the fallopian tubes rather than leaving the body with the menstrual flow. Diagnosis is by pelvic examination or laparoscopy. Treatment, which depends on the severity of the disease, may include a course of oral contraceptives, or danazol if the patient is trying to conceive. In severe cases surgical removal of the cysts or hysterectomyhysterectomy
, surgical removal of the uterus. A hysterectomy may involve removal of the uterus only or additional removal of the cervix (base of the uterus), fallopian tubes (salpingectomy), and ovaries (oophorectomy).
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 may be performed.

The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a gynecological disorder characterized by the tumorlike growth in various organs of endometrioid tissue that structurally and functionally resembles the uterine mucous membrane, or endometrium. The disease generally develops in women between the ages of 30 and 50. Its cause has not been established. One theory is that the condition is caused by the migration of endometrial tissue through blood vessels and the uterine tubes to pelvic organs and other parts of the body. A distinction is made between endometriosis interna (endometrial growths in internal genital organs—most often the uterus and ovaries) and endometriosis externa (growths outside the uterus—in the umbilicus, perineum, intestine, and elsewhere).

Endometriosis is characterized by cyclical changes in the endometrioid masses and by hemorrhages in focuses of the growths during menstruation. Pain is felt before and during menstruation. Endometriosis of the uterus, also known as adenomyosis, intensifies and prolongs menstrual bleeding. The condition may result in sterility. Endometriosis is usually treated by hormonal preparations and uterine agents; some cases require surgery or radiotherapy.


Baskakov, V. P. Endometriozy. Leningrad, 1966.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


The presence of endometrial tissue in abnormal locations, including the uterine wall, ovaries, or extragenital sites.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
A spokesperson from Endometriosis UK said: "As it's a hidden condition, it can be hard for those with the disease to get others to understand or believe the level of pain they are suffering from.
But Emma Cox, CEO of Endometriosis UK, warns a much bigger study would be needed to validate the findings.
(12) Endometriosis pain is progressive, typically cyclic, and can extend beyond the 3-day early follicular phase timeframe associated with primary dysmenorrhea.
Difference between healthy uterus and uterus with Endometriosis
WHAT EXACTLY IS ENDOMETRIOSIS? "ENDOMETRIOSIS occurs when the tissue lining a woman's uterus (called the endometrium) grows in other areas of the body - for example, in the Fallopian tubes, on the ovaries, or in the tissue lining the pelvis," explains Amer.
"It's important to note that pain during sex can come from a variety of causes, so you should see your GP to get this checked out regardless of whether or not you think endometriosis is the root cause." | Subfertility: Some women with endometriosis will experience difficulty in becoming pregnant, says Amer.
Over time and in the shadow of technical and instrumental progress in laparoscopy, this technique turned to the gold standard manner for the treatment of endometriosis.
Canadian Specialist Hospital, one of the top multi-speciality hospitals located in the Abu Hail region of Dubai, was recently accredited by the British Society for Gynaecological Endoscopy (BSGE) for its endometriosis centre.
Thus, it appears reasonable an eventual contribution of some NAT2 polymorphisms in the pathogenesis of endometriosis, in which the role oxidative stress (to which the systemic biotransformation of endogenous or exogenous substances may take part) has been largely demonstrated (3).
Endometriosis is a common gynecologic problem in women of reproductive age.
Featuring a foreword by world renowned endometriosis expert Dr.