endoneurium


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Related to endoneurium: perineurium

endoneurium

[‚en·dō′nu̇r·ē·əm]
(histology)
Connective tissue fibers surrounding and joining the individual fibers of a nerve trunk.
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In Grade 3, axonal degeneration and loss of endoneurium may occur, and nerve fiber continuity recovery may be incomplete.
Common to all head and neck tumours including skin cancers, nerve sheath spread via the endoneurium, perineurium or perineural lymphatics requires meticulous attention to the paths of the Vth and VIIth nerves and their branches.
Collagen is present within the onion bulbs, and the endoneurium contains an abundant mucinous matrix.
Following the presentation of bacterial or viral epitopes by macrophages, T cells become activated and penetrate the endoneurium, where they engage epitopes on abaxonal Schwann cells, thereby triggering a cytokine cascade [3].