endonuclease


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endonuclease

[¦en·dō′nü·klē‚ās]
(biochemistry)
Any of a group of enzymes which degrade deoxyribonucleic acid or ribonucleic acid molecules by attaching nucleotide linkages within the polynucleotide chain.
References in periodicals archive ?
The endonuclease enables the virus to trick someone into producing viral proteins, which join into new viruses that spread the infection.
The assay includes sham reactions containing no endonuclease to correct for variation in DNA input, allowing assessment of the degree of methylation via quantification of the cut (and thus unmethylated) DNA molecules.
Jude researchers engineered a version of the endonuclease designed to enable them to readily determine whether compounds would block the active site.
These mutations respectively prevent plasmid lost through endonuclease activity and plasmid DNA recombination.
Isolation and Evaluation of endonucleases in apoptotic activity of DNA in Ischemic Injury and Reperfusion injury of rat Hepatocyts.
2008) greatly facilitated optimization of the key by allowing us to perform virtual restriction endonuclease digestion (VRED) analyses, which saved time by eliminating much of the laboratory-intense trial-and-error usually associated with identifying informative restriction endonucleases.
Elimination of HDs by the T7 endonuclease I (Lowell 2000) demands strict experimental conditions with respect to enzyme concentration and incubation time which differ from sample to sample and can not be predicted (Qiu et al.
REA, ribotyping and PCR ribotyping: Restriction endonuclease analysis of genomic DNA with Hind III produced six REA patterns among 60 isolates (DI: 76.
35) Danna, K and D Nathans, 'Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae', Proceedings of the National Academy of Sciences USA, vol.
A analise de DNA cromossomico, apos digestao por enzima de restricao (restriction endonuclease analysis--REA), tem sido usada ha varios anos como ferramenta epidemiologica para estudo de surtos de doencas de origem viral ou bacteriana (Destro, 1995; Aarestrup, 2004).
A mutation site in the ITS1 region among BF cirrhosae and other species of BF has been found and can be recognized by the restriction endonuclease SmaI.
However, similar patterns of genome fragments were observed among all strains following restriction endonuclease analysis using the enzyme HpaII.