endosome


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endosome

[′en·də‚sōm]
(cell and molecular biology)
A mass of chromatin near the center of a vesicular nucleus.
(invertebrate zoology)
The inner layer of certain sponges.
References in periodicals archive ?
Exosomes can be formed by endocytosis of the early endosome membrane, having a unique orientation of the involuted cytoplasmic side (16,17) (Figure 1).
When LFn is attached to a complex of seven PAs, it is carried into the cell via formation of an endosome.
Free ferrous iron released from Tf in the endosome enters into cytoplasm via DMT1 on the endosomal membrane.
But to move to the next stage of infection, the virus must fuse with the endosome and spill its DNA into the cell.
The fluorescence intensity (QDs) of cells gradually decreased and was highly concentrated in endosomes, suggesting intracellular degradation of QDs.
The researchers found that endosomes carrying crocidolite fibers 5 micrometers or smaller quickly begin speeding toward the cell nucleus via microtubules -- elaborate, filamentous roadways along which the cell shuttles its inner "vehicles.
If snapin cannot function properly, then dynein is unable to collect the endosome and transport it to the lysosome for disposal.
In the study, using the cells from individuals with Down syndrome that are genetically predisposed to developing Alzheimer's disease, we showed that elevated levels of BCTF, independent of AB, cause a specific pattern of endosome defects with similar pathology of brain cells in Alzheimer's disease," said Ying Jiang, lead author and clinical instructor in the Department of Psychiatry at NYU Langone Medical Center.
In a third model, it is proposed that FIFE limits iron uptake by preventing complete release of iron from the HFE:TfR:Tf-Fe complex in the endosome [Fig.
TfR binds diferric transferrin, and the receptor-transferren complex is internalized into an endosome, where the iron is transferred to the cytosol.
GAPDH distributed in the cell membrane of the endosome mainly reacted in the macromolecules transport, the cytoplasm GAPDH involved in glycolysis metabolism and mainly produced energy (ATP), this kind of GAPDH can bind with the 5'UTR, 3'UTR mRNA in order to control gene expression through the transcriptional regulation and the endonuclear GAPDH can also control gene expression through the regulation of transcriptional, even more the GAPDH can transmit the genetic information through the replication of DNA and also can be passed on DNA repair maintain genomic stability (Sirover et al.
Inside the cells, the internalized complex in the endosome is acidified by a vacuolar [H.