enkephalin


Also found in: Dictionary, Thesaurus, Medical, Acronyms, Wikipedia.

enkephalin

(ĕnkĕf`əlĭn), one of several naturally occurring morphinelike substances (endorphinsendorphins
, neurotransmitters found in the brain that have pain-relieving properties similar to morphine. There are three major types of endorphins: beta endorpins, found primarily in the pituitary gland; and enkephalins and dynorphin, both distributed throughout the nervous
..... Click the link for more information.
) released from nerve endings of the central nervous system and the adrenal medulla. They act as analgesics and sedatives in the body and appear to affect mood and motivation.

enkephalin

[en′kef·ə·lən]
(biochemistry)
A mixture of two polypeptides isolated from the brain; central mode of action is an inhibition of neurotransmitter release.
References in periodicals archive ?
Pharmacology of enkephalins inhibitors: animal and human studies.
It's not that enkephalins or similar drugs make the rats like the chocolates more, the researchers say, but rather that the brain chemicals increase their desire and impulse to eat them.
Enkephalin is an endorphin with similar properties to opium.
In vitro effects of a synethetic enkephalin analogue (D-Met2,Pro5)-enkephalinamide on the hypothalamus-pituitary--testis function in rats.
Activation of the pain control system increases the concentration of beta endorphin, enkephalin, serotonin and norepinephrine levels in the brain tissue and plasma, thus creating an analgesic effect, as well as many others.
The Phase II study has been designed to evaluate NP2 Enkephalin for the treatment of severe and chronic cancer pain.
In other work by George and colleagues (1991), they concluded that a relative lack of enkephalin peptides trans-synaptically, possibly resulting from enhanced enkephalin degradation, might contribute to increased alcohol consumption in C57Bl/6J mice.
Ultrastructural localization of enkephalin and u-opioid receptors in the rat ventral tegmental area.
Tears include a powerful hormone, leucine enkephalin, which regulates pain and other hormones which regulate stress.
Effects of chronic lithium on enkephalin systems and pain responsiveness.
"In addition to this newly acquired Endomorphin technology, and our exclusive licenses for GAD, we also have an ongoing clinical development program with Enkephalin," saidsays Elisabeth Lindner, President and CEO of Diamyd Medical.