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Related to Enterokinase: secretin, enterokinase deficiency


An enzyme which catalyzes the conversion of trypsinogen to trypsin.



a proteolytic enzyme of the class of endopeptidases. Enterokinase is a complex protein containing carbohydrates (glycoprotein). It has been discovered in man and some other mammals. The enzyme is secreted by cells of the mucosa of the duodenum into the lumen of the intestine, where it activates trypsinogen, which enters through the pancreatic duct. The enzyme trypsin thus formed activates trypsinogen and all the other proteolytic enzymes of pancreatic secretion. The direct participation of enterokinase in the digestion of food is insignificant, since only an extremely small quantity is present.

References in periodicals archive ?
Opt, codon-optimized; WT, wild-type; AA, animo acids; AP leader, signal peptide of alkaline protease; ASASA, a linker; DDDDK, enterokinase site; His-tag, 6- histidine tag.
Final analysis of the cassette, using sequencing, showed successful cloning and correct orientation of construct, downstream of enterokinase (EK) cleavage site (data not shown).
64 ng/L, and we observed no cross-reactivity or interference with atrial natriuretic peptide (ANP), enterokinase, human airway trypsinlike protease, hepsin, LDL receptor, matriptase, spinesin, or seipins.
com)-- AnaSpec, EGT Group is pleased to announce the release of two assay kits for quantitating enterokinase enzymatic activity - the SensoLyte[R] 520 and SensoLyte[R] Rh110 Enterokinase Activity Assay Kits.
Trypsinogen in the intestinal homogenate was first converted into trypsin by Enterokinase.