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An enzyme which catalyzes the conversion of trypsinogen to trypsin.



a proteolytic enzyme of the class of endopeptidases. Enterokinase is a complex protein containing carbohydrates (glycoprotein). It has been discovered in man and some other mammals. The enzyme is secreted by cells of the mucosa of the duodenum into the lumen of the intestine, where it activates trypsinogen, which enters through the pancreatic duct. The enzyme trypsin thus formed activates trypsinogen and all the other proteolytic enzymes of pancreatic secretion. The direct participation of enterokinase in the digestion of food is insignificant, since only an extremely small quantity is present.

References in periodicals archive ?
Itzik Harosh, explained that enteropeptidase is a peripheral enzyme localized on the epithelial surface of the duodenum.
A novel, orally administered enteropeptidase inhibitor shows very promising results in vivo.