Evolutionary trajectory of the VP1 gene of human enterovirus 71
genogroup B and C viruses.
Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71
vaccine in children in China: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Virology, epidemiology, pathogenesis, and control of enterovirus 71
. Lancet Infect Dis 2010; 10:778-90.
Yoshida et al., "Outbreak of central nervous system disease associated with hand, foot, and mouth disease in Japan during the summer of 2000: detection and molecular epidemiology of enterovirus 71
," Microbiology and Immunology, vol.
Regulation of host responses and viral replication by the mitogen-activated protein kinases in intestinal epithelial cells infected with Enterovirus 71
. Virus Res 2015; 197: 75-84, doi: 10.1016/ j.virusres.2014.12.016.
The main etiologic agent in conjunctival samples was found to be Adenovirus (46/62, 74.2%) followed by Enterovirus 70 (4/62, 6.4%) and Enterovirus 71
Davis, "Neurological manifestations of enterovirus 71
infection in children during an outbreak of hand, foot, and mouth disease in Western Australia," Clinical Infectious Diseases, vol.
The company stated Enterovirus 71
, or EV71, causes Hand, Foot and Mouth Disease (HFMD).
The strains of enterovirus 71
has been associated with significant morbidity and fatality.
An emerging recombinant human enterovirus 71
responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China.
(EV71) is a positive-stranded RNA genome and belongs to a member of the species A, Enterovirus genus, Picornaviridae family .