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Any disease affecting neurons.



a functional weakness of the nervous system accompanied by a decrease in the absolute threshold (also called the stimulus, or sensitivity, threshold); the condition is frequently congenital.

Neuropathy arises as a disturbance in the function of the autonomic nervous system owing to deleterious influences on the fetus as a whole (for example, infection in the pregnant mother, trauma, or poisoning) or on the individual embryonic cells (as occurs when the parents suffer from alcoholism). Family circumstances, upbringing, and illnesses suffered by the infant play a role in the pathogenesis of neuropathy. The symptoms usually emerge in childhood or adolescence. When neuropathy occurs in early childhood, disturbances of sleep and appetite are most characteristic; the infant has difficulty in falling asleep, awakes easily, suckles poorly, and frequently spits up. Later, vomiting occurs, and either diarrhea or constipation develop.

From the preschool years on, increased general excitability and the rapid onset of fatigue and exhaustion are observed, in addition to continued disturbances of sleep and appetite. Children who suffer from neuropathy blush easily in response to irritation. Motor hyperactivity, nervous tics, and stammering are frequent. In adolescence, autonomic-vascular instability becomes more acute, as evidenced by frequently occurring nervous palpitation, abrupt shifts in blood pressure, headaches, dizzy spells, and fainting spells. The prognosis is favorable, with the neuropathic symptoms usually disappearing with age.


Simson, T. Nevropatii, psikhopatii i reaktivnye sostoianiia mladencheskogo vozrasta. Moscow-Leningrad, 1929.
Sukhareva, G. E. Klinicheskie lektsii po psikhiatrii detskogo vozrasta, vol. 2. Moscow, 1959.


References in periodicals archive ?
2) It is the most prevalent entrapment neuropathy worldwide with significant negative effects on the quality of life of individuals suffering from the condition.
In the case of suspected entrapment neuropathy, electrodiagnosis is part of the first line of investigations.
However, they lead to formation of entrapment neuropathy by the adverse effects they create in nerve metabolism as in diabetes.
The subjects' diagnoses included entrapment neuropathy (n = 51) and radiculopathy (n = 57).
Two patients (8%) showed features of entrapment neuropathy of median nerve i.
have been described a familial case of calcification of STSL affecting a 58 year old man and his son, who had STSL calcification causing entrapment neuropathy of the suprascapular nerve, clinical symptoms of pain, weakness of the external rotation and abduction, and atrophy of the supraspinatus muscle (Weinfeld et al.
Less common manifestations include cerebellar dysfunction, isolated dementia of the frontal lobe type, extrapyramidal signs, seizures, an amyotrophic lateral sclerosis-like disorder, and entrapment neuropathy.
CTS also has been classified as a compression or entrapment neuropathy (Goodgold, 1981).
Keywords: Gout, Cubital tunnel syndrome, Entrapment neuropathy, Uric acid.
Piriformis syndrome is an entrapment neuropathy of the sciatic nerve at the level of the piriformis muscle.